Advances in clinical chemistry

by Makowski, Gregory S.

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Title Statements

Full title :Advances in clinical chemistry.

Edition Statements

Publication Date:©2015

Publication Statements

Publisher(s):Academic Press
Place of Publication:Amsterdam, [Netherlands]
Language:eng
Publication Date:©2015

Notes

Description based upon print version of record.

3.1. Trastuzumab: Mechanism of Action

The Physical Object

Description:1 online resource (336 p.).

Edition Identifiers

ISBN:0128033177, 9780128033173, 0128033169, 9780128033166
oclc:on1112940365
LC Classification:RB40
Dewey Decimal:616.07/56

3.1. High-Performance Liquid Chromatography with 125I3.1.1. Preparation of the 125I Reagent; 3.1.2. Binding Characteristics of the 125I Reagent; 3.1.3. HPLC Separation and Quantification of PlsCho and PlsEtn; 3.1.4. Improved 125I-HPLC Method; 3.1.5. Extraction and Stability; 3.2. Liquid Chromatography-Tandem Mass Spectrometry; 3.2.1. Extraction of Lipids; 3.2.2. Standards for LC-MS/MS; 3.2.3. Method Parameters; 3.2.4. Analysis by LC-MS/MS; 3.3. Enzymatic Assay; 3.3.1. PlsEtn Assay Principle; 3.3.2. PLA1 from S. albidoflavus NA297; 3.3.3. LyPlsase Activity Assay

3.3.4. Cloning and Expression of P. putida KT2440 LyPlsase3.3.5. Partial Purification of P. putida KT2440 LyPlsase; 3.3.6. Substrate Specificity and Primary Structure of P. putida KT2440 LyPlsase; 3.3.7. PlsEtn Assay; 4. Clinical Utility; 4.1. Middle-Aged Normal Subjects; 4.1.1. Characteristics of Serum Egp; 4.1.2. Egp and Various Risk Factors; 4.2. Coronary Artery Disease; 4.2.1. Characteristics of Serum Egp in CAD; 4.2.2. Relationship Between Egp and Atherogenic Parameters; 4.3. Elderly Dementia; 4.3.1. CD and Serum PlsEtn; 5. Conclusion; Acknowledgments; References

Chapter Three: Monitoring Trastuzumab Resistance and C…