Advances in molecular toxicology

by Fishbein, James C. Heilman, Jacqueline M.

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Title Statements

Full title :Advances in molecular toxicology. / James C. Fishbein, Department of Chemistry and Biochemistry, University of Maryland, Baltimore County, Baltimore, Maryland, USA, Jacqueline M. Heilman, Exponent, Inc., Washington, District of Columbia, USA.

Edition Statements

Publication Date:2015.
Edition:First edition

Publication Statements

Publisher(s):Elsevier
Place of Publication:Amsterdam
Language:eng
Publication Date:2015.

Notes

Description based upon print version of record.

3.3.2. In vitro humoral immune responses

The Physical Object

Description:1 online resource (293 p.).

Edition Identifiers

ISBN:0128024305, 9780128024300, 0128022299, 9780128022290
oclc:on1162070635
LC Classification:RA1220.3

Front Cover; Advances in Molecular Toxicology; Copyright; Contents; Contributors; Preface; Chapter One: Endocrine-Disrupting Chemicals with Estrogenicity Posing the Risk of Cancer Progression in Estrogen-Responsi...; 1. Introduction; 2. Signaling Pathways of Estrogen in Estrogen-Responsive Cancers; 2.1. Genomic pathway; 2.2. Nongenomic pathway; 2.3. Ligand-independent signaling pathway; 3. Diverse Effects of EDCs in Estrogen-Responsive Cancers; 3.1. Bisphenol A; 3.2. Nonylphenol and octylphenol; 3.3. Methoxychlor; 3.4. Triclosan; 3.5. Phytoestrogens; 4. Conclusions; Acknowledgments

5.4. Characteristics of arsenic-binding proteins5.5. Mechanistic studies of arsenic binding to vicinal thiol-containing proteins; 5.6. Arsenic interactions with thiol-containing transcription factors; 6. Conclusions; References; Chapter Three: Molecular Mechanisms of Arsenic Toxicity; 1. Introduction; 2. Arsenic Methylation Pathway and Its Products; 2.1. Classic and new alternative arsenic metabolism pathways; 2.2. Methylation is an enzymatically catalyzed reaction and its intermediate products are more reactive and toxic than in...

2.3. Methylation reaction of arsenic is both activation and detoxific…