Age-Related Macular Degeneration

The value of Age-Related Macular Degeneration has stood the test of time, but progress in both basic and clinical ophthalmology has been relentless, mandating the need for an updated book. This second edition focuses on the pathophysiology and the epidemiology of age-related macular degeneration (AMD), the clinical features and management of dry and wet AMD, imaging techniques, and medical therapy for both non-neovascular AMD and neovascular AMD. It describes both clinically validated and experimental therapies as well as rehabilitation technology, and presents strategies to prevent the progression of non-exudative AMD. Results from current clinical trials are also included. New chapters in this edition cover: Genetics and treatment Oxidative stress and its relation to the pathophysiology of AMD and CNV (choroidal neovascularizationâ€"a common symptom of wet AMD) Polypoidal choroidal vasculopathy Microperimetry and psychophysical testing and ways to track geographic atrophy progression Non-VEGF pathways Retinal stem cells.

Front Cover -- Contents -- Contributors -- Foreword -- Preface -- 1. Histopathology of age-related macular degeneration -- 2. Immunology of age-related macular degeneration -- 3. Genetics of age-related macular degeneration -- 4. Choroidal neovascularization: VEGF pathways -- 5. Risk factors for age-related macular degeneration and choroidal neovascularization -- 6. Oxidative stress -- 7. Geographic atrophy -- 8. Non-neovascular age-related macular degeneration -- 9. Neovascular age-related macular degeneration -- 10. Polypoidal choroidal vasculopathy -- 11. Variants of neovascular age-related macular degeneration: Type 3 neovascularization (intraretinal neovascularization or retinal angiomatous proliferation) -- 12. Role of fluorescein angiography in the treatment of age-related macular degeneration -- 13. Use of indocyanine green angiography in the management of age-related macular degeneration -- 14. Role of optical coherence tomography in the evaluation of age-related macular degeneration -- 15. How to analyze OCT images for management of neovascular age-related macular degeneration -- 16. Fundus autofl uorescence imaging in age-related macular degeneration -- 17. Microperimet…