Title Statements

  • Full title :Antiplatelet agents / edited by Paolo Gresele, Gustav V.R Born, Carlo Patrono, Clive P. Page.

Edition Statements

  • Publication Date:2012.

Publication Statements

The Physical Object

  • Description:1 Online-Ressource

Edition Identifiers

  • ISBN:9783642294235, 3642294235, 9783642294228, 3642294227
  • DOI:10.1007/978-3-642-29423-5
  • oclc:ocn811317039
  • LC Classification:RM1-950
  • Dewey Decimal:615

Table of Contents

Pathophysiology -- Platelets: production, morphology and ultrastructure -- Platelet receptors -- Platelet signaling -- Platelet interaction with the vessel wall -- Platelets in atherosclerosis and thrombosis -- Pharmacology -- Aspirin and other COX-1 inhibitors -- Thienopyridines and other ADP-receptor antagonists -- Glycoprotein IIb/IIIa antagonists -- Targeting phosphodiesterases in anti-platelet therapy -- PAR-1 inhibitors: a novel class of antiplatelet agents for the treatment of patients with atherothrombosis -- Thromboxane receptors antagonists and/or synthase inhibitors -- Inhibitors of the interaction between von Willebrand factor and platelet GPIb/IX/V -- Inhibitors of the interactions between collagen and its receptors on platelets -- Intracellular signaling as a potential target for antiplatelet therapy -- Novel targets for platelet inhibition -- Variability of platelet indices and function: acquired and genetic factors -- Small RNAs as potential platelet therapeutics -- Pharmacological modulation of the inflammatory actions of platelets -- Therapy -- Role of laboratory monitoring in antiplatelet therapy -- Antiplatelet agents in ischemic heart disease -- Antiplatelet t…

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