Aptamers in biotechnology

by Bahnemann, J., (Janina) Urmann, Katharina Walter, Johanna-Gabriela

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Title Statements

Full title :Aptamers in biotechnology / Katharina Urmann, Johanna-Gabriela Walter, editors ; with contributions by J. Bahnemann [and 15 others].

Summary

This book reviews the development, characterization and applications of aptamers in different areas of biotechnology ranging from therapeutics to diagnostics and protein purification. Hailed as chemical antibodies, these single-stranded nucleic acid receptors were predicted to supersede antibodies in traditional assays, such as ELISA, within a short time. While this has yet to happen, readers will find in this book a deep insight into the progress of aptamer technology and a critical discussion about the limitations that need to be overcome in order to find wider acceptance and use outside of the still relatively small aptamer-community. This book covers all aspects of aptamer generation and application for the aptamer-experienced reader and curious novice alike, with the addition of an industry perspective on the future of aptamer-use in biotechnology.

Edition Statements

Publication Date:2020

Publication Statements

Publisher(s):Springer
Place of Publication:Cham, Switzerland
Language:eng
Publication Date:2020

The Physical Object

Description:vii, 215 pages : : illustrations (black and white, and colour) ; : 24 cm

Edition Identifiers

ISBN:9783030540609, 303054060X
oclc:on1159471011
LC Classification:QP625.O47
Dewey Decimal:572.8/5

Biophysical Characterization of Aptamer-Target Interactions -- Impedimetric Aptamer-based Biosensors: Principles and Techniques -- Impedimetric Aptamer-based Biosensors: Applications -- Aptamer-based affinity chromatography for protein extraction and purification -- Aptamers in diagnostic and molecular imaging applications -- Aptamer-modified nanoparticles in medical applications -- Defining Target Product Profiles (TPPs) for Aptamer based diagnostics.

Subjects

Aptamères nucléotidiques Aptamers, Nucleotide Biosensing Techniques Molecular Diagnostic Techniques Oligonucléotides -- Biotechnologie Oligonucleotides -- Biotechnology