Barrett's Esophagus

Barrett's Esophagus gives an extensive overview written by the world's leading experts covering the epidemiology, gastroenterology and surgery, as well as the molecular basis of: the precursor lesions leading to the development of Barrett's epithelium; the unique characteristics of Barrett's esophagus; the consequences of malignant degeneration, i.e. adenocarcinoma. All aspects in terms of diagnosis, secondary prevention, multimodality, medical and surgical treatment are elucidated.

Norman Barrett and the esophagus -- Section 1: Normal Anatomy and Physiology of the Esophagus -- 1.1 Anatomy and embryology of the esophagus -- 1.2 Cell biology of the esophageal epithelium -- 1.3 Normal physiology of the esophagus -- 1.4 Pathophysiology of gastro-esophageal reflux disease -- Section 2: Gastro-Esophageal Reflux Disease -- 2.1 The natural history of gastro-esophageal reflux disease -- 2.2 Helicobacter pylori and reflux disease -- 2.3 Acid and bile in the esophagus -- 2.4 Endoscopie classification of gastro-esophageal reflux disease -- 2.5 Optimal surgical therapy for anti reflux disease -- 2.6 Surgical treatment of duodeno-gastro esophageal reflux -- Section 3: Barrett's Esophagus -- Diagnosis -- 3.1 Histopathology of Barrett's esophagus -- 3.2 The metaplasia-dysplasia-carcinoma sequence of Barrett's esophagus -- 3.3 Genetic alterations -- 3.4 Endoscopic surveillance -- 3.5 Short segment Barrett's esophagus and intestinal metaplasia at the gastro-esophageal junction -- Section 4: Barrett's Esophagus -- Treatment -- 4.1 Prevention of cancer by control of reflux -- 4.2 Prevention of cancer in Barrett's by ablation -- 4.3 The role of ablation in the management of high…