Bayesian inference for gene expression and proteomics
by Do, Kim-Anh Müller, Peter Vannucci, Marina
The interdisciplinary nature of bioinformatics presents a research challenge in integrating concepts, methods, software and multiplatform data. Although there have been rapid developments in new technology and an inundation of statistical methods for addressing other types of high-throughput data, such as proteomic profiles that arise from mass spectrometry experiments. This book discusses the development and application of Bayesian methods in the analysis of high-throughput bioinformatics data…
Read More ↓Title Statements
- Full title :Bayesian inference for gene expression and proteomics / edited by Kim-Anh Do, Peter Müller, Marina Vannucci.
Summary
The interdisciplinary nature of bioinformatics presents a research challenge in integrating concepts, methods, software and multiplatform data. Although there have been rapid developments in new technology and an inundation of statistical methods for addressing other types of high-throughput data, such as proteomic profiles that arise from mass spectrometry experiments. This book discusses the development and application of Bayesian methods in the analysis of high-throughput bioinformatics data that arise from medical, in particular, cancer research, as well as molecular and structural biology. The Bayesian approach has the advantage that evidence can be easily and flexibly incorporated into statistical methods. A basic overview of the biological and technical principles behind multi-platform high-throughput experimentation is followed by expert reviews of Bayesian methodology, tools and software for single group inference, group comparisons, classification and clustering, motif discovery and regulatory networks, and Bayesian networks and gene interactions.
Read More ↓Edition Statements
- Publication Date:2006.
Publication Statements
- Publisher(s):Cambridge University Press
- Place of Publication:Cambridge
- Language:eng
- Publication Date:2006.
The Physical Object
- Description:1 online resource (xviii, 437 pages) : : PDF file(s).
Edition Identifiers
- ISBN:9780511584589, 051158458X, 9780521860925, 052186092X, 9781107636989, 1107636981, 9780521860925
- oclc:on1170898327
- LC Classification:QH450
- Dewey Decimal:572.8/6501519542
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