Bone morphogenic protein

Bone morphogenic protein

by Litwack, Gerald

Type Book
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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on Bone Morp…

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Title Statements

  • Full title :Bone morphogenic protein.

Summary

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on Bone Morphogenic Protein.

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Edition Statements

  • Publication Date:2015.

Publication Statements

  • Publisher(s):Academic Press
  • Place of Publication:Amsterdam
  • Language:eng
  • Publication Date:2015.

The Physical Object

  • Description:1 online resource

Edition Identifiers

  • ISBN:9780128025925, 0128025921, 0128024429, 9780128024423
  • oclc:ocn931603845
  • LC Classification:QP552.B65
  • Dewey Decimal:612.75

Table of Contents

Front Cover; Bone Morphogenic Protein; Copyright; Former Editors; Contents; Contributors; Preface; Chapter One: Mechanisms of BMP-Receptor Interaction and Activation; 1. Evolutionary Expansion and Diversification of the Transforming Growth Factor Ý Superfamily; 2. Phylogenetic Analysis Reveals Four Functional Subfamilies for TGFÝ Ligands; 3. Expression as Protease-Activated Proproteins and a Cystine-Knot Motif in the C-Terminal Mature Region as Key Features ... ; 4. TGFÝ Receptor Activation and Its Downstream Signaling Cascade; 5. Too Few Receptors for Too Many Ligands Lead to Promiscuity.

6. Molecular Mechanisms to Ensure Ligand-Receptor Promiscuity and Specificity: The Concept of Multiple Hot Spots of Binding7. Molecular Mechanisms to Ensure Ligand-Receptor Promiscuity and Specificity: The Concept of Structural Adaptability; 8. Consequences of Promiscuity and Specificity in the TGFÝ Superfamily: Conclusions; References; Chapter Two: The Bone Morphogenetic Proteins and Their Antagonists; 1. Bone Morphogenetic Proteins; 2. BMP Antagonist Proteins; 2.1. Chordin Family; 2.2. Follistatin and Follistatin-Like Proteins; 2.3. Noggin; 2.4. Twisted Gastrulation.

3. Cerberus and Dan Fami…

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