Brain tumors

Brain tumors

by Ali-Osman, Francis

Type Book
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A comprehensive guide for both scientists and clinicians to recent advances in our understanding of the cellular and molecular processes involved in the initiation, progression, and clinical and biological behavior of brain tumors. The authors review the latest findings on the molecular biology, genetics, epidemiology, and pathology of brain tumors, detailing new knowledge about molecular profiling, molecular pathology and classification, in vitro and in vivo brain tumor models, brain metastasi…

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Title Statements

  • Full title :Brain tumors / edited by Francis Ali-Osman.

Summary

A comprehensive guide for both scientists and clinicians to recent advances in our understanding of the cellular and molecular processes involved in the initiation, progression, and clinical and biological behavior of brain tumors. The authors review the latest findings on the molecular biology, genetics, epidemiology, and pathology of brain tumors, detailing new knowledge about molecular profiling, molecular pathology and classification, in vitro and in vivo brain tumor models, brain metastasis, and progenitor cell biology. They also discuss in depth the cellular and genetic pathways involved in brain oncogenesis, malignant progression, and therapeutic response, highlighting oncogenes and tumor suppressor genes, DNA damage and repair, invasion and migration, cell cycle, growth factors, signaling, apoptosis, and developmental biology. The discussion of brain tumor therapy focuses on advances in pharmacological thinking, therapeutic modalities, novel therapeutic targets, ratio.

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Edition Statements

  • Publication Date:©2005.

Publication Statements

  • Publisher(s):Humana Press
  • Place of Publication:Totowa, N.J
  • Language:eng
  • Publication Date:©2005.

The Physical Object

  • Description:xi, 393 pages : : illustrations ; : 26 cm.

Edition Identifiers

  • ISBN:1588290425, 9781588290427, 1592598439, 9781592598434
  • oclc:ocm56066492
  • LC Classification:RC280.B7
  • Dewey Decimal:616.99/481

Table of Contents

Epidemiology of brain tumors / Randa El-Zein, Melissa Bondy, and Margaret Wrensch -- Molecular genetics of tumors of the central nervous system / C. David James -- Molecular pathology of nervous system tumors / Catherine L. Nutt [and others] -- Genetic modeling of glioma formation in mice / Martin Begemann [and others] -- Biology of brain metastasis / Minsoo Kang [and others] -- Analysis of neural precursor cells in the context of origin of brain tumors, their treatment, and repair of treatment-associated damage / Mark Noble and Joerg Dietrich -- Biology of primitive neuroectodermal tumors / John R. Hill, Shoichiro Ohta, and Mark A. Israel -- Molecular and cellular biology of the blood-brain barrier and its characteristics in brain tumors / Helga E. de Vries [and others] -- Immune regulation in the brain : lessons from autoimmunity and implications for brain tumor therapy / Lois A. Lampson -- Genetic pathways in the evolution of gliomas / Hiroko Ohgaki and Paul Kleihues -- DNA damage and repair in the therapeutic response of tumors of the central nervous system / Henry S. Friedman, M. Eileen Dolan, and Francis Ali-Osman -- Role of urokinase-type plasminogen activator receptor in h…

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