Cancer and its Management

Now in its seventh edition, this highly-regarded book is designed as an introductory and reference text on the principles of diagnosis, staging, and treatment of tumors. As for the last 6 editions of the book, the aim and scope of the new edition are once again to provide a thorough yet reasonably brief account of the whole field of oncology, focusing on the latest principles of cancer management. The book is already well established, having been first published in 1986 and in continuous print since then. The authors are rightfully proud of their strong legacy of providing carefully revised new editions of this standard and well-received cancer text for audiences in the UK and abroad. Oncology is a very rapidly changing speciality, with many new treatments and even treatment modalities coming on stream with bewildering speed. Besides a thorough general updating of the text, figures, and tables, the new seventh edition adds a new chapter on Molecular Targeted Therapy, making the book 30 chapters in total. This accessible and practical resource is invaluable to trainees and specialists alike in oncology, palliative care and general medicine, as well as specialist nurses, general practitioners, medical students, and professions allied to medicine.

Combinations of surgery and radiotherapy [39-41].

Cover -- Title Page -- Copyright -- Contents -- Preface -- Acknowedgements -- Abbreviations -- Chapter 1 The modern management of cancer: an introductory note -- References -- Further reading -- Chapter 2 Epidemiology, cure, treatment trials and screening -- Terminology and methods in epidemiology -- Geographical distribution of cancer -- Temporal distribution of cancer -- Causes of cancer suggested by epidemiological studies -- Inhaled carcinogens -- Lifestyle and diet -- Ionizing irradiation -- Occupational factors -- Viral causes -- Cancer statistics -- Survival data and determination of cure in cancer -- Assessment of results: trials of treatment -- Randomized trials -- Informed consent -- Non-randomized studies of treatment -- Screening for cancer -- Secondary prevention of cancer -- References -- Further reading -- Chapter 3 Biology of cancer -- Carcinogenesis: persistent genetic damage -- Chemical carcinogens -- Ionizing and ultraviolet irradiation -- Initiators and promoters in carcinogenesis -- Repair of damage to DNA induced by carcinogens -- Inherited defects involving DNA damage or repair processes that predispose to cancer -- Viral causes of cancer -- RNA viruses -- D…