Title Statements
- Full title :Chromosomal instability and aging : basic science and clinical implications / edited by Fuki M. Hisama, George M. Martin.
Summary
This text examines the relationship between DNA damage and repair, cellular senescence, genomic instability and ageing. It includes in-depth discussions of various types of DNA damage, the DNA repair network, and cellular responses to genetic damage.
Read More ↓Edition Statements
- Publication Date:©2003.
Publication Statements
- Publisher(s):Marcel Dekker
- Place of Publication:New York
- Language:eng
- Publication Date:©2003.
The Physical Object
- Description:1 online resource (xviii, 579 pages) : : illustrations (some color)
Edition Identifiers
- ISBN:0824747305, 9780824747305, 9780203911709, 0203911709
- oclc:ocm52854788
- LC Classification:QP86
- Dewey Decimal:612.6/7
Table of Contents
Foreword; Preface; Contents; Contributors; Introduction; Overview of Chromosomal Instability and Aging Mechanisms; Cellular Senescence; Telomeric Shortening and Replicative Aging; Telomeric Regulation in Eukaryotic Cells; Role of Ku at the Telomere; Chromosomal Instability in Normative Aging; Chromatin, Aging, and Cellular Senescence; Werner Syndrome; Bloom Syndrome: Genetic, Cellular, and Molecular Features as Compared to Werner Syndrome; Molecular Biology of Rothmund-Thomson Syndrome; Hutchinson-Gilford Progeria Syndrome; Ataxia-Telangiectasia; Nijmegen Breakage Syndrome.
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