Clinical bioinformatics

by Trent, R. J.

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Title Statements

Full title :Clinical bioinformatics / edited by Ronald Trent, Department of Medical Genomics, Royal Prince Alfred Hospital and Sydney Medical School, University of Sydney, Camperdown, Australia.

Summary

In Clinical Bioinformatics, Second Edition, leading experts in the field provide a series of articles focusing on software applications used to translate information into outcomes of clinical relevance. Recent developments in omics, such as increasingly sophisticated analytic platforms allowing changes in diagnostic strategies from the traditional focus on single or small number of analytes to what might be possible when large numbers or all analytes are measured, are now impacting patient care. Covering such topics as gene discovery, gene function (microarrays), DNA sequencing, online approaches and resources, and informatics in clinical practice, this volume concisely yet thoroughly explores this cutting-edge subject. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Clinical Bioinformatics, Second Edition serves as an ideal guide for scientists and health professionals working in genetics and genomics.

Edition Statements

Publication Date:2014
Edition:Second edition

Publication Statements

Publisher(s):Humana Press
Place of Publication:New York
Language:eng
Publication Date:2014

The Physical Object

Description:xi, 326 pages : : illustrations (some color) ; : 24 cm

Edition Identifiers

ISBN:9781493908462, 1493908464
oclc:ocn888946513
LC Classification:QH324.2
Dewey Decimal:610.285

From the phenotype to the genotype via bioinformatics / Cali E. Willet and Calire M. Wade -- Production and analytic bioinformatics for next-generation DNA sequencing / Richard James, Nigel Allcock -- Analyzing the metabolome / Fracnis G. Bowling and Mervyn Thomas -- Statistical perspectives for Genome-Wide Association Studies (GWAS) / Jennifer H. Barrett, John C. Taylor, and Mark M. Iles -- Bioinformatics challenges in Genome-Wide Association Studies (GWAS) / Rishika De, William S. Bush, and Jason H. Morre -- Studying cancer genomics through next-generation DNA sequencing and bioinformatics / Maraia A. Doyle, Jason LI, Ken Doig, Andrew Fellowes, and Stephen Q. Wong -- Using bioinformatics tools to study the role of microRNA in cancer / Fabio Passetti, Natasha Andressa Noguiera Jorge, and Alan Durham -- Chromosome microarrays in diagnostic testing : interpreting the genomic data / Greg B. Peters and Mark D. Pertile -- Bioinformatics approach to understanding interacting pathways in neuropsychiatric disorders / Ali Alawieh, Zahraa Sabra, Amaly Nokkari, Atlal El-Assaad, Stefania Mondello, Fadi Zaraket, Bilal Fadlallah, and Firas H. Kobeissy -- Pathogen genome bioinformatics / Vitali…

Subjects

Bio-informatique Bioinformatics Computational Biology Computational Biology -- methods Databases, Genetic Genomics Genomics -- Data processing Génomique Génomique -- Informatique Laboratory Manual Laboratory manuals Manuels de laboratoire Medical Informatics Computing Sequence Analysis, DNA