Clinical trial data analysis using R

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"With examples based on the authors' 30 years of real-world experience in many areas of clinical drug development, this book provides a thorough presentation of clinical trial methodology. It presents detailed step-by-step illustrations on the implementation of the open-source software R. Case studies demonstrate how to select the appropriate clinical trial data. The authors introduce the corresponding biostatistical analysis methods, followed by the step-by-step data analysis using R. They als…

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Title Statements

Full title :Clinical trial data analysis using R / Ding-Geng (Din) Chen, Karl E. Peace.

Summary

Edition Statements

Publication Date:©2011.

Publication Statements

Publisher(s):CRC Press
Place of Publication:Boca Raton, Florida
Language:eng
Publication Date:©2011.

The Physical Object

Description:1 online resource (xxiii, 363 pages) : : illustrations

Edition Identifiers

ISBN:9781439840214, 1439840210, 0429151322, 9780429151323
DOI:10.1201/b10478
oclc:ocn740896962
LC Classification:R853.C55
Dewey Decimal:615.50724

1. Introduction to R -- 2. Overview of clinical trials -- 3. Treatment comparisons in clinical trials -- 4. Treatment comparisons in clinical trials with covariates -- 5. Analysis of clinical trials with time-to-event endpoints -- 6. Analysis of data from longitudinal clinical trials -- 7. Sample size determination and power calculation in clinical trials -- 8. Meta-analysis of clinical trials -- 9. Bayesian analysis methods in clinical trials -- 10. Analysis of bioequivalence clinical trials -- 11. Analysis of adverse events in clinical trials -- 12. Analysis of DNA microarrays in clinical trials.

Subjects

Clinical trials -- Statistical methods Clinical Trials as Topic -- methods Études cliniques -- Méthodes statistiqu… Logiciels MEDICAL -- Pharmacology R (Computer program language) R (Langage de programmation) software Statistics Statistics as Topic Statistiques