Computer-aided vaccine design

by Chuan, Tong Joo Ranganathan, Shoba

Type Book

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Title Statements

Full title :Computer-aided vaccine design / Joo Chuan Tong and Shoba Ranganathan

Summary

Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. "Computer-Aided Vaccine Design" is a comprehensive introduction to this exciting field of study. "Computer-Aided Vaccine Design" is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. The book is of interest to computational biologists who would like to understand more about the biological concepts related to the field of computational immunology. This title is essential for any biologists who wants to understand methods of computer-aided vaccine design and how the different computer programs work. Available data sources and publicly available software are amply described, with detailed analysis of their strengths and weaknesses. Theoretical concepts and practical examples of database design and development for a virtual screening campaign are provided. Underlying algorithms and assumptions are clearly explained for the non-specialist. Theoretical foundations are linked to the design of a virtual screening campaign, with an emphasis on potential problems and solutions