Title Statements
- Full title :Computing for biologists : python programming and principles / Ran Libeskind-Hadas, Department of Computer Science, Harvey Mudd College, Eliot Bush, Department of Biology, Harvey Mudd College.
Summary
Computing is revolutionizing the practice of biology. This book, which assumes no prior computing experience, provides students with the tools to write their own Python programs and to understand fundamental concepts in computational biology and bioinformatics. Each major part of the book begins with a compelling biological question, followed by the algorithmic ideas and programming tools necessary to explore it: the origins of pathogenicity are examined using gene finding, the evolutionary history of sex determination systems is studied using sequence alignment, and the origin of modern humans is addressed using phylogenetic methods. In addition to providing general programming skills, this book explores the design of efficient algorithms, simulation, NP-hardness, and the maximum likelihood method, among other key concepts and methods.
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- Publication Date:©2014
Publication Statements
- Publisher(s):Cambridge University Press
- Place of Publication:Cambridge
- Language:eng
- Publication Date:©2014
The Physical Object
- Description:x, 207 pages : : illustrations (some color), map (some color) ; : 26 cm
Edition Identifiers
- ISBN:9781107042827, 1107042828, 9781107642188, 1107642183
- oclc:ocn880831140
- LC Classification:QH324.2
- Dewey Decimal:570.285
Table of Contents
Meet Python -- Part I : Python versus pathogens. Computing GC content -- Pathogenicity islands -- Open reading frames and genes -- Finding genes (at last!) -- Part II : Sequence alignment and sex determination. Recursion -- The use-ir-or-lose-it principle -- Dictionaries, memoization, and speed -- Sequence alignment and the evolution of sex chromosomes -- Part III : Phlyogenetic reconstruction and the origin of modern humans. Representing and working with trees -- Drawing trees -- The UPGMA algorithm -- Part IV : Additional topics. RNA secondary structure prediction -- Gene regulatory networks and the maximum likelihood method -- Birds, bees, and genetic algorithms -- Where to go from here.
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