Dermatotoxicology

Reflecting the embryonic state of the field, the first edition of Dermatoxicology, published in 1977, numbered 567 pages. Now the foundational reference in dermal toxicology, this seventh edition consists of 1,032 pages and defines what was once a largely intuitive field but has evolved into an established science of metrics and mechanisms. Updated and expanded to reflect the latest developments, the seventh edition includes fundamental information on the mechanisms of action of toxic substances on the skin and practical information on the many methods for evaluating dermal toxicity. Unparalleled in its coverage and broad in scope, with the addition of 34 new chapters, this volume keeps pace with the expanding science. A perennial bestseller, this definitive text explores the latest developments in the field. With contributions from leading international experts, it continues the tradition of providing unsurpassed theoretical and practical guidance.

Front cover -- Contents -- Preface -- Editors -- Contributors -- Chapter 1. Pharmacogenetics and Dermatology -- Chapter 2. Ethnic Differences in Skin Properties: Objective Data -- Chapter 3. Occlusion and Barrier Function -- Chapter 4. Anatomical Factors Affecting Barrier Function -- Chapter 5. Percutaneous Penetration Enhancers: Overview -- Chapter 6. Percutaneous Absorption of Complex Chemical Mixtures -- Chapter 7. Percutaneous Absorption: Short-Term Exposure, Lag Time, Multiple Exposures, Model Variations, and Absorption from Clothing -- Chapter 8. Percutaneous Absorption: 7 Roles of Lipids -- Chapter 9. Chemical Partitioning into Powdered Human Stratum Corneum: A Useful In Vitro Model for Studying Interactions of Chemicals and Human Skin -- Chapter 10. Sensitive Skin -- Chapter 11. Transdermal Drug Delivery System: An Overview -- Chapter 12. Iontophoresis: From Historical Perspective to Its Place in Modern Medicine -- Chapter 13. Irritant Dermatitis: Clinical Heterogeneity and Contributing Factors -- Chapter 14. Systemic Contact Dermatitis -- Chapter 15. Allergic Contact Dermatitis -- Chapter 16. Mechanisms in Irritant and Allergic Contact Dermatitis -- Chapter 17. Occupation…