DNA replication

Widely hailed upon its publication in 1980, the first edition of this book is regarded as a classic of modern science. Kornberg's insights and his descriptions of the enzymology of DNA replication drew together the many aspects of the field within one authorative volume and made it the standard reference in the field. Now this distinctive work has been completely revised to reflect current research and interpretations. The authors have created and exceptional second edition that provides the reader with up-to-date coverage of DNA replication and related cellular processes- including excellent summaries of recent work on replication in eukaryotes and bacteria. Other new features of the second edition include: Expanded coverage of DNA polymerases, primases and primosomes, helicases, topiosomerases, DNA-binding protein, plasmids and organelles, and chromosomal origins; The latest on mechanisms of replication initiation in prokaryotes and their essential recapitulation in eukaryotic systems; Summaries of the replication cycles of many prokaryotic and eukayotic viruses and plasmids, presented in the framework of their lifecycles; Related aspects of RNA synthesis and DNA repair, modification, recombination, and chromosomal segregation. -- from Back Cover.

DNA Structure and function -- Biosynthesis of DNA precursors -- DNA synthesis -- DNA polymerase I of E. coli -- Prokaryotic DNA polymerases other than E. coli Pol I -- Eukaryotic DNA polymerases -- RNA polymerases -- Primases, primosomes, and priming -- Ligases and Polynucleotide kinases -- DNA-binding protiens -- DNA Helicases -- Topoisomerases -- Deoxyribonucleases -- Inhibitors of replicaton -- Replication mechanisms and operations -- Genome origins -- Bacterial DNA viruses -- Plasmids and organelles -- Animal DNA viruses amd retroviruses -- Regulation of Chromosomal replication and cell division -- Repair, recombination, transformation, restriction, and modification -- Synthesis of genes and chromosomes.