Title Statements
- Full title :Drug Eruptions.
Edition Statements
- Publication Date:©2022.
Publication Statements
- Publisher(s):Springer International Publishing AG
- Place of Publication:Cham
- Language:eng
- Publication Date:©2022.
Notes
3 Clinical Assessment.
The Physical Object
- Description:1 online resource (347 pages).
Edition Identifiers
- ISBN:9783031093883, 3031093887
- oclc:on1351270843
- LC Classification:RL1-803
- Dewey Decimal:615.7042
Table of Contents
Intro -- Preface -- Introduction -- Clinical Approach to a Patient with a Cutaneous ADR -- Drug Causality in Cutaneous ADRs -- Classification of the Cutaneous ADRs -- Mechanistic Classification -- Drug Hypersensitivity Reactions -- Non-hypersensitivity -- Phenotypic Classification -- Contents -- Contributors -- Part I: General Considerations -- Pharmacogenetics of Cutaneous Adverse Drug Reactions -- 1 Introduction -- 2 Abacavir Hypersensitivity and HLA-B*57:01 -- 3 Carbamazepine Hypersensitivity -- 3.1 Carbamazepine Metabolism Genes -- 3.2 Carbamazepine and HLA Alleles -- HLA-B*15:02 -- HLA-A*31:01 -- 3.3 Carbamazepine and Other HLA Alleles -- 3.4 Carbamazepine and T Cell Receptor Variation -- 4 Aromatic Antiepileptics and Hypersensitivity -- 5 Allopurinol Hypersensitivity and HLA-B*58:01 -- 6 Dapsone Hypersensitivity -- 7 Other Drugs -- 8 Discussion -- References -- Mechanisms of Drug Hypersensitivity -- 1 Introduction -- 2 Models of Drug Antigen Presentation -- 3 Genetic Factors in Drug Hypersensitivity -- 3.1 Genetic Factor in Immediate-Type Drug Hypersensitivity -- 3.2 Genetic Factor in Delayed-Type Drug Hypersensitivity -- Allopurinol -- Aromatic Anticonvulsants -- Abacavir -…
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