Endocrine disruption modeling

Endocrine disruption modeling

by Devillers, James

Type Book
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Uses Computational Tools to Simulate Endocrine Disruption Phenomena Endocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the extensive research of an international panel of contributors from industry, academia, and regulatory agencies, this is the first book devoted to using computer tools to better understand and simulate the mul…

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Title Statements

  • Full title :Endocrine disruption modeling / edited by James Devillers.

Summary

Uses Computational Tools to Simulate Endocrine Disruption Phenomena Endocrine Disruption Modeling provides a practical overview of the current approaches for modeling endocrine activity and the related potential adverse effects they may induce on environmental and human health. Based on the extensive research of an international panel of contributors from industry, academia, and regulatory agencies, this is the first book devoted to using computer tools to better understand and simulate the multifaceted aspects of endocrine disruption in humans and wildlife. Explores Diverse Modeling Techniques and Applications This up-to-date resource focuses on xenobiotics that are accidentally released into the environment with the potential to disturb the normal functioning of the endocrine system of invertebrates and vertebrates but also on the specific agro-chemistry design of chemicals that take control of insect endocrine systems. A comprehensive research reference, Endocrine Disruption Modeling provides a collection of computational strategies to model these structurally diverse chemicals. It concludes with a review of the available e-resources in the field, rounding out the book's task-oriented approach to future EDC discovery. Endocrine Disruption Modeling is the first book in the QSAR in Environmental and Health Sciences series (James Devillers, j.devillers@ctis.fr).

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Edition Statements

  • Publication Date:©2009.

Publication Statements

  • Publisher(s):CRC Press
  • Place of Publication:Boca Raton
  • Language:eng
  • Publication Date:©2009.

The Physical Object

  • Description:1 online resource (404 pages, 7 unnumbered pages of plates) : : illustrations (some color).

Edition Identifiers

  • ISBN:1322611130, 9781322611136, 9781420076363, 1420076361, 1420076353, 9781420076356
  • oclc:ocn901282541
  • LC Classification:RA1224.2
  • Dewey Decimal:615/.190072

Table of Contents

In silico methods for modeling endocrine disruption / James Devillers -- Mechanisms of endocrine disruptions : a tentative overview / Jean-Marc Porcher, James Devillers, and Nathalie Marchand-Geneste -- Population dynamics modeling : a tool for environmental risk assessment of endocrine disrupting chemicals / Andrew R. Brown [and others] -- Application of pharmacokinetic modeling to understand the mechanism of action of endocrine disrupting chemicals / James Devillers -- Comparative modeling review of nuclear hormone receptor superfamily / Nathalie Marchand-Geneste and James Devillers -- The U.S. Food and Drug Administration's (FDA) Endocrine Disruptor Knowledge Base (EDKB) : lessons learned in QSAR modeling and applications / Hong Fang [and others] -- A structure-activity relationship (SAR) analysis for the identification of environmental estrogens : the categorical-SAR (cat-SAR) approach / Albert R. Cunningham [and others].

Kohonen and counterpropagation neural networks employed for modeling endocrine disruptors / Marjana Novič and Marjan Vračko -- Quantitative spectrometric data-activity relationships (QSDAR) models of endocrine disruptor binding activities / Richard D. Beger,…

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  • Endocrine Disruption Modeling (QSAR in Environmen…

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