Endothelium

Endothelium

by Khalil, Raouf A.

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Title Statements

  • Full title :Endothelium / edited by Raouf A. Khalil.

Edition Statements

  • Publication Date:©2016
  • Edition:First edition

Publication Statements

  • Publisher(s):Academic Press
  • Place of Publication:Amsterdam, [Netherlands]
  • Language:eng
  • Publication Date:©2016

Notes

Description based upon print version of record.

Chapter Four: Epoxyeicosatrienoic Acids and 20-Hydroxyeicosatetraenoic Acid on Endothelial and Vascular Function

The Physical Object

  • Description:1 online resource (464 p.).

Edition Identifiers

  • ISBN:0128044152, 9780128044155, 0128043962, 9780128043967
  • oclc:on1159611573
  • LC Classification:QP88.45
  • Dewey Decimal:599.0821

Table of Contents

Front Cover; Endothelium; Copyright; Contents; Contributors; Preface; Chapter One: The Endothelium-Dependent Nitric Oxide-cGMP Pathway; 1. Introduction; 2. Part I: NO-sGC Signaling; 2.1. Endothelial Dysfunction and NO Deficiency; 2.2. eNOS (NOS-3) Uncoupling; 2.3. Endogenous Inhibitors of eNOS (NOS-3); 2.4. NO Receptor: sGC; 2.5. Phosphodiesterases; 3. Part II: NO-sGC Pathway as a Therapeutic Target for Cardiovascular Diseases; 3.1. Therapeutic Approach for Pulmonary Hypertension Therapy; 3.1.1. PAH in Newborn: Inhaled NO; 3.1.2. Adult PAH: PDE5 Inhibitors; 3.1.3. Adult PAH: sGC Modulators

3.2. Therapeutic Approach for Heart Disease3.2.1. HF: PDE5 Inhibitors; 3.2.2. HF: sGC Modulators; 4. Part III: Epigenetics Regulation of NO-sGC Pathway Components in the Cardiovascular System; 4.1. Outline of Epigenetic Regulation; 4.2. Epigenetic Regulation of eNOS (NOS-3); 4.3. Epigenetic Regulation of iNOS; 4.4. Epigenetic Regulation of nNOS; 4.5. Epigenetic Regulation of sGC; 4.6. Nitric Oxide Modulating Epigenetics Pathways; 5. Conclusion; Acknowledgments; Conflict of Interest; References; Chapter Two: Transcriptional and Posttranslational Regulation of eNOS in the Endothelium

1. Introduc…

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Subjects

Endothelium

Writers

Khalil, Raouf A. Khalil, Raouf A.

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