Epilepsy

The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7 - 9 years, and the 'success' rate of translation was very recently listed as less than one half. The success rate is defined as results in human studies which were predicted i.

Epilepsy; Foreword; Preface; Acknowledgments; Contents; Part I: Introduction; Chapter 1: World Health Concerns; Chapter 2: Metabolism and Epilepsy; Chapter 3: Epidemiology of Epilepsy; Part II: Generalized Seizures; Chapter 4: Animal Models of Absence Seizures; Chapter 5: Absence Seizures in Humans; Chapter 6: Tonic Seizures in Animals; Chapter 7: Human Tonic Epilepsy; Chapter 8: Atonic Seizures; Chapter 9: Tonic-Clonic Epilepsy in Animals; Chapter 10: Tonic-Clonic Epilepsy in Humans; Chapter 11: Juvenile Myoclonic Epilepsy in Animals; Chapter 12: Juvenile Myoclonic Epilepsy in Humans.

Part III: Partial EpilepsiesChapter 13: Simple Partial Seizures; Chapter 14: Models of Complex Partial Seizures: Animal Studies; Chapter 15: Complex Partial Epilepsy in Humans; Chapter 16: Nocturnal Epilepsy Animal Models; Chapter 17: Human Nocturnal Epilepsy; Part IV: Miscellaneous Epilepsies; Chapter 18: Febrile Seizures; Chapter 19: Infantile Spasms; Chapter 20: Gelastic Epilepsy; Chapter 21: Landau-Kleffner Syndrome; Chapter 22: Rasmussen's Syndrome; Chapter 23: Status Epilepticus; Chapter 24: Epilepsy and Autism; Chapter 25: Reactive Epilepsy: Phenylketonuria; Part V: Medical Treatment.

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