Ex-vivo and In-vivo Optical Molecular Pathology

The result of a unique collaboration between clinicians and physicists, this book provides an unparalleled overview of a new generation of diagnostic tools in clinical pathology. The introductory three chapters cover the present status and limitations of currently used methods, followed by an outline of promising novel spectroscopy-based technologies either under development or recently available on the market. The input from both physicists developing these new methods as well as routine clinicians familiar with practical aspects and medical relevance guarantees that this practical work i.

3.4.5.3 Trapped Cells in Microfluidic Chips.

Ex-vivo and In-vivo Optical Molecular Pathology; Contents; List of Contributors; Preface; Chapter 1 Clinical Pathology; 1.1 Introduction; 1.2 Pathology as a Medical and Research Discipline; 1.3 Historical Perspectives; 1.4 Specimens; 1.4.1 Biopsies, Resections, and Cytology; 1.5 Conventional Diagnostic Methods in Pathology; 1.5.1 Cytology; 1.5.2 Histology; 1.5.3 Microscopy; 1.5.4 Intraoperative Assessment (Frozen Section Examination); 1.5.5 Why Pathologists Do Not Like Frozen Tissue Examination?; 1.5.6 Microdissection.

1.6 Nonconventional (Ancillary) Diagnostic Methods in Pathology (Molecular Assessment of Tissues)1.6.1 In Situ Reactions; 1.6.1.1 Immunofluorescence (IF); 1.6.1.2 Immunohistochemistry (IHC); 1.6.1.3 Fluorescent In Situ Hybridization (FISH); 1.6.2 Non-In Situ Methods; 1.7 Summary of Major Terms in Clinical Pathology; 1.7.1 Injury and Adaptation; 1.7.2 Inflammation and Repair; 1.7.3 Neoplastic Diseases; 1.8 Limitations of Clinical and Diagnostic Pathology; 1.8.1 Prediction of Tumor Behavior; 1.8.2 Diagnosis of Tumor Origin in a Case with Metastatic Tumor Disease.

1.8.3 Individualized Medicine and Targeted TherapyFurther Readings; Chapter 2 Clinical Endoscopy in Gast…