Glycopeptide antibiotics

by Nagarajan, Ramakrishnan

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Title Statements

Full title :Glycopeptide antibiotics / edited by Ramakrishnan Nagarajan.

Summary

"Describing all known assays used to discover new glycopeptide antibiotics, this outstanding reference discusses practical techniques for screening, isolating, and analyzing glycopeptide antibiotics - correlating structure-activity relationships with the mode of action." "Classifying glycopeptide antibiotics according to differences in the chemical structure of the core heptapeptide aglycone, Glycopeptide Antibiotics examines every relevant chemical aspect of the carbohydrate components of glycopeptide antibodies ... details the purification of glycopeptide antibodies from fermentation broths ... contains an exhaustive survey of synthetic routes to the 3-amino-2,3,6-trideoxyhexoses ... reviews advances made towards the total synthesis of vancomycin and other similar chemical structures ... investigates the analytical quantitation, characterization, pharmacokinetics, clinical uses, and safety profile of vancomycin and related glycopeptides ... delineates the discovery, chemistry, antimicrobial activity, pharmacokinetics, and toxicology of teicoplanin ... explores the problem of resistance with glycopeptide antibodies ... and much more." "Exhaustively referenced furnishing over 1650 literature citations, Glycopeptide Antibiotics is an invaluable resource for industrial, clinical, and research pharmacists; pharmacologists; organic and medicinal chemists; pharmaceutical research and development managers; microbiologists; and graduate students in these disciplines."--BOOK JACKET.

Edition Statements

Publication Date:©1994.

Publication Statements

Publisher(s):M. Dekker
Place of Publication:New York
Language:eng
Publication Date:©1994.

The Physical Object

Description:xiv, 423 pages : : illustrations ; : 24 cm.

Edition Identifiers

ISBN:0824791932, 9780824791933
oclc:ocm29848265
LC Classification:RM409
Dewey Decimal:615/.329

Glycopeptides: classification, occurrence and discovery / Raymond C. Yao and Louise W. Crandall -- Separation methodology / Robert D. Sitrin and Gail Folena-Wasserman -- Approaches to the synthesis of the vancomycin aglycones / David E. Evans and Keith M. DeVries -- Chemistry of carbohydrate components / Ferenc Sztaricskai and Istvan Pelyvas-Ferenczik -- Structure-activity relationships of vancomycin antibiotics / Ramakrishnan Nagarajan -- Resistance and mode of action / Thalia I. Nicas and Norris E. Allen -- Analytical quantitation and characterization / Eugene L. Inman and C.L. Winely -- Teicoplanin / Beth P. Goldstein, Rita Rosina and Francesco Parenti -- Vancomycin: a clinical overview / Michael L. Zeckel and James R. Woodworth.

Subjects

Anti-Bacterial Agents antibacterial agents Antibactériens antibiotica Antibiotikum ANTIBIOTIQUES Antibiotiques glycopeptidiques Aufsatzsammlung Glycopeptide antibiotics Glycopeptides Glykopeptide Vancomycin Vancomycine