Heart development

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The developing heart is the first functional organ, and its proper formation and function is essential for life. This volume compiles the exciting new advances that have been made in understanding the regulation of heart development, the genes and pathways involved, and the impact these have in heart disease. A stellar collection of scientists tackles an important facet of heart development, providing a comprehensive set of reviews. Cutting-edge science Authority of contributors Exciting field …

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Title Statements

Full title :Heart development / edited by Benoit G. Bruneau.

Summary

Edition Statements

Publication Date:2012.
Edition:1st ed

Publication Statements

Publisher(s):Academic Press
Place of Publication:San Diego, Calif
Language:eng
Publication Date:2012.

The Physical Object

Description:1 online resource (xvi, 391 pages, 16 unnumbered pages of plates) : : illustrations (some color).

Edition Identifiers

ISBN:9780123877864, 0123877865, 9780123877901, 0123877903, 1280582901, 9781280582905, 9786613612687, 6613612685
oclc:ocn785414378
LC Classification:QL951
Dewey Decimal:612.1/7

Front Cover; Heart Development; Copyright; Contents; Contributors; Preface; Chapter 1: Life Before Nkx2.5: Cardiovascular Progenitor Cells: Embryonic Origins and Development; 1 Introduction; 2 Early Heart Development: Is It as Simple as Location, Location, Location?; 3 CPCs: The Building Blocks of the Heart; 4 CPC Determination: The Quest for ""Cardiod""; 5 Signaling Pathways and CPC Fate; 6 A Moving Story: Early CPC Migration and Fate; 7 Changing the Program: CPC Relationship to Reprogramming and Transdifferentiation; 8 Conclusions: Future Questions and Possible Applications; Acknowledgments

6 The Second Heart Field in Vertebrate Evolution7 The Second Heart Field as Part of a Cardiocraniofacial Developmental Field; 8 Perspectives; Acknowledgments; References; Chapter 3: An Unauthorized Biography of the Second Heart Field and a Pioneer/Scaffold Model for Cardiac Development; 1 Introduction; 2 Subpharyngeal Cardiac Precursors; 2.1 Using soft words and hard arguments; 2.1.1 Strong; 2.1.2 Light; 3 Models of Cardiac Development; 3.1 Mosaic, regulative or a patterned mosaic?; 3.2 Retrospective fate mapping highlights the intrinsic unity of the cardiac progenitor population

4 A Histor…

Subjects

Cœur -- Croissance Coeur -- Maladies Cœur -- Physiopathologie Heart -- Abnormalities Heart -- Growth Heart -- growth & development Heart -- Pathophysiology Heart -- physiology Heart Defects, Congenital Heart Diseases Heart Diseases -- pathology MEDICAL -- Physiology SCIENCE -- Life Sciences