Hematopoiesis

by Bresnick, Emery

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Title Statements

Full title :Hematopoiesis / Emery Bresnick.

Edition Statements

Publication Date:2016.

Publication Statements

Publisher(s):Elsevier Science
Place of Publication:San Diego, CA, USA
Language:eng
Publication Date:2016.

The Physical Object

Description:1 ressource en ligne (310 pages)

Edition Identifiers

ISBN:9780128033197, 0128033193
oclc:on1016010238
LC Classification:QP92
Dewey Decimal:573.1/55

Front Cover; Hematopoiesis; Copyright; Contents; Contributors; Preface; Chapter One: Regulation of Blood Stem Cell Development; 1. Introduction; 1.1. HSC Generation; 1.2. Tracking Hematopoietic Cell Generation from Embryonic Endothelium; 1.3. Regulation of Hemogenic Endothelium; 1.4. Hemogenic Transcriptional Program; 1.5. Reprogramming; References; Chapter Two: Hematopoietic Stem Cell and Its Bone Marrow Niche; 1. Introduction; 2. Evolution of the Stem Cell Niche Concept; 3. Location Matters; 4. Cellular Participants in the Bone Marrow Microenvironment; 4.1. Osteolineage Cells

4.2. Perivascular Cells4.3. Endothelial Cells; 4.4. Adipocytes; 4.5. Macrophages; 5. The Sympathetic Nervous System; 6. HSC Mobilization from the BM Niche; 7. Niche of Hematopoietic Malignancies; 8. Perspectives; References; Chapter Three: The Hematopoietic Stem and Progenitor Cell Cistrome: GATA Factor-Dependent cis-Regulatory Mechanisms; 1. cis-Regulatory Mechanisms; 2. GATA Factor Interactions with DNA and Chromatin; 2.1. Sequence Requirements; 2.2. Genomic and Bioinformatics Analysis; 2.3. Discovery and Validation of Enhancers Controlling HSPCs

3. Components of Scl/TAL1 and GATA Factor Complexes at E-…