High-density lipoproteins: structure, metabolism, function, and therapeutics
by Chapman, M. John Kontush, Anatol
A complete guide to the role of high-density lipoproteins (HDL) in new and emerging therapies. With high-density lipoproteins (HDL) playing an increasing role in cardiovascular disease prevention, there is a growing need for an in-depth look at HDL and its clinical value. This book summarizes the current state of knowledge in the field, providing for the first time a comprehensive, systematic, stylistically coherent, and up-to-date review of the composition, structure, heterogeneity, metabolism…
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- Full title :High-density lipoproteins : structure, metabolism, function, and therapeutics / edited by Anatol Kontush, M. John Chapman ; illustrations by Alexander Marienko.
Summary
A complete guide to the role of high-density lipoproteins (HDL) in new and emerging therapies. With high-density lipoproteins (HDL) playing an increasing role in cardiovascular disease prevention, there is a growing need for an in-depth look at HDL and its clinical value. This book summarizes the current state of knowledge in the field, providing for the first time a comprehensive, systematic, stylistically coherent, and up-to-date review of the composition, structure, heterogeneity, metabolism, epidemiology, genetics, and function of HDL. Divided into three main parts, first examines normal HDL particles, then describes defective HDL, and finally addresses the therapeutic normalization of subnormal levels and defective biological activities of this lipoprotein class. The book highlights the functional properties of HDL, which are relevant to the pathophysiology of atherosclerosis and thrombosis, and discusses the compositional and metabolic heterogeneity of HDL particles. Readers will come away with a clear understanding of the role of HDL in biological processes, the potential value of functional HDL as a therapeutic target, and how current and emerging therapies are poised to influence the treatment of heart disease in the future.
Read More ↓Edition Statements
- Publication Date:©2012.
Publication Statements
- Publisher(s):John Wiley & Sons, Inc
- Place of Publication:Hoboken, N.J
- Language:eng
- Publication Date:©2012.
The Physical Object
- Description:xxxvi, 605 pages : : illustrations (some color) ; : 24 cm
Edition Identifiers
- ISBN:9780470408216, 0470408219
- oclc:ocn743275863
- LC Classification:QP552.L5
- Dewey Decimal:572/.68
Table of Contents
Normal functional HDL -- Functionally defective HDL -- Therapeutic normalisation of subnormal levels and defective biological activities of HDL.
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