High-throughput synthesis: principles and practices

by Sucholeiki, Irving

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Title Statements

Full title :High-throughput synthesis : principles and practices / edited by Irving Sucholeiki.

Edition Statements

Publication Date:©2001.

Publication Statements

Publisher(s):M. Dekker
Place of Publication:New York
Language:eng
Publication Date:©2001.

The Physical Object

Description:xxi, 366 pages : : illustrations ; : 24 cm

Edition Identifiers

ISBN:0824702565, 9780824702564, 9781420056518, 1420056514
oclc:ocm45248220
LC Classification:QD262
Dewey Decimal:547/.2

An introduction to solid phase organic synthesis / Irving Sucholeiki -- Methods of analysis to determine the progress of a chemical reaction on solid support / J. Manuel Perez -- High-throughput organic synthesis : a perspective looking back on 10 years of combinatorial chemistry / Michael R. Pavia -- Techniques and strategies for producing compound libraries for biological screening / Stephen R. Wilson, Kathryn Reinhard -- Case study 4-1. A [gamma]-turn mimetic library : development and production / Petr Kocis [and others] -- Case study 4-2. Production of an [alpha]-ketoamide-containing library via convergent parallel synthesis / Alan P. Kaplan, Carmen M. Baldino -- Case study 4-3. Manual solid phase synthesis of a fully encoded, 46,656-member benzimidazole library / David Tumelty [and others] -- Case study 4-4. Protease substrate specificity mapping using membrane-bound peptides / Richard A. Laursen, Caizhi Zhu, Yongjun Duan -- Case study 4-5. Characterization of the epitope specificity of antibodies using membrane-bound peptides / Richard A. Laursen, Zhengxin Wang -- Case study 4-6. Rapid parallel synthesis utilizing microwave irradiation / Brian M. Glass, Andrew P. Combs -- Hi…