Human Embryonic Stem Cells in Development

Human Embryonic Stem Cells in Development, Volume 129, the latest release in the Current Topics in Developmental Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as recapitulating pancreas development from human embryonic stem cells in a dish, modeling mammalian gastrulation with embryonic stem cells, and a section on what stem cells tell us about human germ cell biology. Each chapter is written by an international board of authors.

VERSEMENT EN LOT.

Front Cover; Human Embryonic Stem Cells in Development; Copyright; Contents; Contributors; Preface; Chapter One: Modeling Mammalian Gastrulation With Embryonic Stem Cells; 1. Introduction; 2. Mathematical Preliminaries; 3. Colony Architecture; 3.1. Growth in Two-Dimensional Micropatterns; 3.2. Three-Dimensional Culture Systems; 4. Spatial Patterning of Cell Fates; 4.1. Micropatterned Two-Dimensional Culture Systems; 4.2. Three-Dimensional Culture Systems; 5. Conclusions; Acknowledgment; References; Chapter Two: What Can Stem Cell Models Tell Us About Human Germ Cell Biology?; 1. Introduction

2. Signaling for Germ Cell Specification in Mammalian Embryos3. Permissive Cell State for Germ Cell Specification in the Embryo; 4. Inducing Germline Competency in Pluripotent Stem Cells; 5. Transcription Factors for Human Germ Cell Specification and Epigenetic Resetting; 6. In Vitro Germ Cell Induction Beyond PGC Specification; 7. Misregulation of Germ Cell Development; 7.1. Germ Cell Tumors; 7.2. Inheritance of Epigenetic Mutations Through the Germline; 7.3. Inheritance of Mitochondria Through the Female Germline; 8. Perspective; Acknowledgments; References; Further Reading

Chapter Three: …