In vitro neurotoxicology: principles and challenges

Type Book

Rate 0.0 /5

Provides new concepts and directions for in vitro assessment of neurotoxicity; functional assays for evaluation of neruotoxicity; interactions of neurons and glia in neurotoxicity; review of endogenous neurotoxic proteins; complementary in vivo/in vitro strategies in neurotoxicology; validation of in vitro models in neurotoxicology; interdisciplinary approach utilizing cell biology, neurophysiology, and risk assessment; annotated bibliography of important review articles, books, and methods man…

Details

Files

Reviews

Download

Title Statements

Full title :In vitro neurotoxicology : principles and challenges / edited by Evelyn Tiffany-Castiglioni.

Summary

Edition Statements

Publication Date:©2004.

Publication Statements

Publisher(s):Humana Press
Place of Publication:Totowa, N.J
Language:eng
Publication Date:©2004.

The Physical Object

Description:xv, 331 pages : : illustrations ; : 24 cm.

Edition Identifiers

ISBN:1588290476, 9781588290472
oclc:ocm52070110
LC Classification:RC347.5
Dewey Decimal:616.8/047

Machine derived contents note: Dedication v -- Foreword vii -- Preface ix -- Contributors xiii -- 1 In Vitro Neurotoxicology: Introduction to Concepts -- Evelyn Tiffany-Castiglioni 1 -- 2 Predictive Value of In Vitro Systems -- for Neurotoxicity Risk Assessment -- Marion Ehrich and David C. Dorman 29 -- 3 Exposure-Dose-Response Paradigm -- as It Relates to Toxicogenomics -- William H. Hanneman, Melvin E. Andersen, -- Marie E. Legare, Christine T. French, -- Tami S. McMullin, Carolyn Broccardo, -- and Ruth E. Billings 41 -- 4 In Vitro Studies of Neurotoxicant Effects -- on Cellular Homeostasis -- Gerald J. Audesirk and Ronald B. Tjalkens 59 -- 5 Role of Apoptosis in Neurotoxicology -- Lori D. White, Sid Hunter, Michael W. Miller, -- Marion Ehrich, and Stanley Barone, Jr 95 -- 6 Impairment of Neurotransmitter Metabolism -- and Function by Neurotoxicants: -- Enzyme Pathways in Neurons and Astroglia -- Michael Aschner and Ursula Sonnewald 133 -- 7 Cell-Type-Specific Responses -- of the Nervous System to Lead -- Evelyn Tiffany-Castiglioni and Yongchang Qian 151 -- 8 Effects of Toxicants on Neural Differentiation -- Stanley Barone, Jr., Prasada R.S. Kodavanti, -- and William R. Mundy 18…

Subjects

Neurotoxicity Syndromes Neurotoxicologie Neurotoxicology Neurotoxins -- toxicity Toxicité in vitro Toxicity testing -- In vitro Toxicity Tests -- methods