Lung transplantation

This book provides a detailed account of the principles and practice of contemporary lung transplantation. An accomplished, international team of contributing authors have combined their expertise to provide scientific developments and clinical knowledge based on their extensive experience. The book covers pulmonary vascular and parenchymal lung disease, which necessitate transplantation, together with all aspects of the multidisciplinary management of lung transplant patients. It concludes by looking at future developments in the treatment of advanced respiratory failure. This multidisciplinary approach makes the publication suitable for several subspecialities in addition to pulmonary medicine and lung transplantation, including haematology, radiology and clinical psychology. It will serve as a valuable source of reference and practical information for medical specialists in transplantation and all those working in thoracic organ transplant units.

Pulmonary disease -- Primary pulmonary hypertension: pathophysiology and therapy -- Genetics of pulmonary hypertension -- Pathology of pulmonary hypertension -- Pulmonary hypertension and the right ventricle -- Emphysema -- Alpha-1-antitrypsin deficiency -- Bronchiectasis -- Cystic fibrosis -- Diffuse lung disease -- Explant pathology -- Lung transplantation -- Overview -- Patient selection and indications for lung transplantation -- Single and bilateral lung transplantation -- Combined heart and lung transplantation -- Anaesthesia and intensive care -- Medical management -- Immunological mechanisms of graft injury -- Pharmacological immunosupression -- Chronic lung allograft dysfunction -- Infectious complications -- Cytomegaloviurs infection -- Imaging -- Transplant pathology -- Haematology -- Psychology -- Current status of lung transplantation -- Future directions -- Tissue engineering -- Xenotransplantation -- Artificial lung.