Meta-research: methods and protocols

by Evangelou, Evangelos

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Title Statements

Full title :Meta-research : methods and protocols / edited by Evangelos Evangelou, Areti Angeliki Veroniki.

Summary

This volume presents state-of-the art design, analysis and integration approaches for biomedical data including novel statistical models for a comprehensive and powerful synthesis and assessment of scientific evidence. Chapters detail principles of systematic reviews, semi-automated tools for systematic searches, fixed- and random-effects meta-analytical models, living systematic reviews, meta-analysis of genetic studies, meta-analysis of pragmatic and explanatory trials, network meta-analysis, and other modern approaches for data synthesis. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Meta- Research : Methods and Protocols book, written by global experts, will introduce the reader in a step-by-step process to the methods of the vital and highly promising field of evidence synthesis.

Edition Statements

Publication Date:copyright 2022

Publication Statements

Publisher(s):Humana Press
Place of Publication:New York, NY
Language:eng
Publication Date:copyright 2022

The Physical Object

Description:1 vol. (XI-318 p.) : : ill. ; : 26 cm.

Edition Identifiers

ISBN:9781071615652 (rel), 1071615653 (rel)
oclc:on1294299610

[Contents] Principles of Systematic Reviews and Meta-analyses. -- Semi-automated Tools for Systematic Searches. -- Fixed- and Random-Effects Models. -- Assessing Heterogeneity in Random-Effects Meta-analysis. -- Performing Meta-analyses with Very Few Studies. -- Systematic Versus Rapid Versus Scoping Reviews. -- Living Systematic Reviews. -- Umbrella Reviews: What They Are and Why We Need Them. -- Meta-analysis of Pragmatic and Explanatory Trials. -- Meta-Analysis of Proportions. -- Meta-Analysis Methods of Diagnostic Test Accuracy Studies. -- Network Meta-Analysis. -- Contrast-Based and Arm-Based Models for Network Meta-Analysis. -- Software to Conduct a Meta-Analysis and Network Meta-Analysis. -- Modeling Multicomponent Interventions in Network Meta-Analysis. -- Practical Considerations and Challenges When Conducting an Individual Participant Data (IPD) Meta-Analysis. -- Individual Patient Data Meta-Analysis and Network Meta-Analysis. -- Challenges in Comparative Meta-Analysis of the Accuracy of Multiple Diagnostic Tests.