Metabolic Flux Analysis: Methods and Protocols
by Blank, Lars M. Krömer, Jens O. Nielsen, Lars K.
"This book is dedicated to Metabolic Flux Analysis in systems that can be studied under metabolic steady-state or pseudo-steady-state conditions, also called stationary approaches. Under these conditions the change of intracellular metabolite concentrations (CMET) as a function of the stoichiometric matrix S and the flux vector v can be approximated to zero. This approximation converts the equations system from a differential to a linear one and greatly simplifies its solution. We hope that thi…
Read More ↓Title Statements
- Full title :Metabolic Flux Analysis : Methods and Protocols / edited by Jens O. Krömer, Lars K. Nielsen, Lars M. Blank.
Summary
"This book is dedicated to Metabolic Flux Analysis in systems that can be studied under metabolic steady-state or pseudo-steady-state conditions, also called stationary approaches. Under these conditions the change of intracellular metabolite concentrations (CMET) as a function of the stoichiometric matrix S and the flux vector v can be approximated to zero. This approximation converts the equations system from a differential to a linear one and greatly simplifies its solution. We hope that this book will open the field of metabolic flux analysis to a wider scientific community by providing helpful tricks to those who want to start a new flux analysis project but are overwhelmed by the complexity of the approach. We tried to break it up into manageable bits of information that can be implemented step by step following the methods chapters provided. The overview chapters are there to explain the necessary basics to get started and also to review what has been achieved within a few model organisms."--Preface, page vi.
Read More ↓Edition Statements
- Publication Date:©2014
Publication Statements
- Publisher(s):Humana Press
- Place of Publication:New York, NY
- Language:eng
- Publication Date:©2014
The Physical Object
- Description:1 online resource (xii, 316 pages) : : illustrations (some color)
Edition Identifiers
- ISBN:9781493911707, 1493911708, 1493911694, 9781493911691
- DOI:10.1007/978-1-4939-1170-7
- oclc:ocn891059613
- LC Classification:QH324.9.M4
- Dewey Decimal:570
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