Microarray methods for drug discovery

by Chittur, Sridar V.

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Title Statements

Full title :Microarray methods for drug discovery / edited by Sridar V. Chittur.

Summary

While the utilization of microarrays for gene expression studies has been widely published, Microarray Methods for Drug Discovery describes the use of this technology for a multitude of other vital applications. Covering the field of drug discovery through its various aspects, including high throughput screening, target identification, drug metabolism and toxicity screening as well as clinical sample handling, this volume also addresses new emerging fields like miRNA profiling, ribonomic and glycomic profiling. All chapters, contributed by experts in the field, follow the highly successful Methods in Molecular Biology series format, which is comprised of brief introductions, lists of required materials and reagents, readily reproducible, step-by-step lab protocols, along with detailed tips on troubleshooting and avoiding known pitfalls, making this book an easy read for investigators at all levels of expertise. Authoritative and cutting-edge, Microarray Methods for Drug Discovery provides an ideal desk reference for scientists who wish to use microarray technology in order to better understand a variety of biological interactions in their respective fields.

Edition Statements

Publication Date:©2010.

Publication Statements

Publisher(s):Humana Press
Place of Publication:New York, N.Y
Language:eng
Publication Date:©2010.

The Physical Object

Description:1 online resource (xi, 284 pages) : : illustrations (some color)

Edition Identifiers

ISBN:9781607616634, 1607616637
DOI:10.1007/978-1-60761-663-4
oclc:ocn606907763
LC Classification:RM301.25
Dewey Decimal:572.8636

Multicenter clinical sample collection for microarray analysis / T.S. Mondala, D.R. Salomon, and S.R. Head -- Isolation of total RNA from transgenic mouse melanoma subsets using fluorescence-activated cell sorting / S. Tighe and M.A. Held -- Microarray analysis of embryonic stem cells and differentiated embryoid bodies / A.C. Zambon and C.S. Barker -- Determination of alternate splicing events using the Affymetrix Exon 1.0 ST arrays / S. Subbaram [and others] -- Profiling microRNA expression with the illumina BeadChip platform / J. Tsao, P. Yau, and N. Winegarden -- TaqMan array cards in pharmaceutical research / D.N. Keys, J.K. Au-Young, and R.A. Fekete -- DMET microarray technology for pharmacogenomics-based personalized medicine / J.K. Burmester [and others] -- The use of microarray technology for cytogenetics / B.A. Bejjani, L.G. Shaffer, and B.C. Ballif -- PCR/LDR/universal array platforms for the diagnosis of infectious disease / M. Pingle [and others] -- RIP-CHIP in drug development / R. Jain [and others] -- ChIPing away at global transcriptional regulation / K. Jackson, J. Paris, and M. Takahashi -- HELP (HpaII tiny fragment enrichment by ligation-mediated PCR) assay for D…

Subjects

Acides nucléiques -- Hybridation Analytical, Diagnostic and Therapeutic … Biological Science Disciplines biological sciences Biomedicine biomedische wetenschappen Chemistry Chemistry Techniques, Analytical Chemistry, Pharmaceutical Chimie Chimie pharmaceutique Criblage à haut débit (Développement de… Disciplines and Occupations Drug development Drug Discovery Drug Evaluation, Preclinical Electronic books Evaluation studies as topic farmacologie Geneeskunde (algemeen)