Modern methods in carbohydrate synthesis

Modern Methods in Carbohydrate Synthesis presents in one volume a sequence of chapters leading from classical methods through to today's newest state-of -the-art technology for oligosaccharide synthesis. It places particular emphasis on the most recent breakthroughs in the field, including emerging technologies for both oligosaccharide and glycoconjugate synthesis. Chapters describing the synthesis of increasingly important glycosidic linkage analogs, as well as the oligosaccharides containing derivatives and analogs of natural sugars are included. While chemical-synthetic methods constitute the major part of the book, completing the volume is a section on the rapidly expanding and important field of enzymatic synthesis, also covering combined chemical and enzymatic synthesis. Chapters are written by leading experts in the field. Wherever possible, methods of synthesis are provided in sufficient detail to allow the reader to implement the techniques described. More than 1700 references are provided in the 21 chapters comprising the book. This volume should provide a wealth of information to a large number of synthetic organic chemists, medicinal chemists, protein chemists, biochemists, glycobiologists and cell biologists, including students in these fields.

1. Twenty Five Years of Carbohydrate Chemistry: An Overview of Oligosaccharide Synthesis / Hans Paulsen -- 2. The Anomeric O-Alkylation and the Trichloroacetimidate Method -- Versatile Strategies for Glycoside Bond Formation / Richard R. Schmidt -- 3. Synthesis of Glycosyl Halides for Oligosaccharide Synthesis Using Dihalogenomethyl Methyl Ethers / Pavol Kovac -- 4. Glycosylation Properties and Reactivity of Thioglycosides, Sulfoxides, and other S-glycosides: Current Scope and Future Prospects / Thomas Norberg -- 5. Phenyl Selenoglycosides as Versatile Glycosylating Agents in Oligosaccharide Synthesis and the Chemical Synthesis of Disaccharides Containing Sulfur and Selenium / Seema Mehta and B. Mario Pinto -- 6. Synthesis and Use of S-Xanthates, Carbohydrate Enol Ethers and Related Derivatives in the Field of Glycosylation / Pierre Sinay and Jean-Maurice Mallet -- 7. n-Pentenyl Glycosides in Oligosaccharide Synthesis / Robert Madsen and Bert Fraser-Reid -- 8. Coupling of Glycals: A New Strategy for the Rapid Assembly of Oligosaccharides / Mark T. Bilodeau and Samuel J. Danishefsky -- 9. Advances in Polymer-Supported Solution Synthesis of Oligosaccharides / Jiri J. Krepinsky -- 10…