Molecular Diagnostics: techniques and applications for the clinical laboratory

Advances in genomic and proteomic profiling of disease have transformed the field of molecular diagnostics, thus leading the way for a major revolution in clinical practice. While the range of tests for disease detection and staging is rapidly expanding, many physicians lack the knowledge required to determine which tests to order and how to interpret results. This handbook provides a complete guide to the use and interpretation of molecular testing in the clinical arena. No other available resource offers this emphasis, comprehensive scope, and practical utility in the clinical setting.

E-bok.

Part I: Introduction and Methodology -- Ch. 1 Quantitative PCR: An Introduction / Marilynn R. Fairfax, Hossein Salimnia -- Ch. 2 Signal Amplification Methods in Molecular Diagnostics / Maura Pieretti -- Ch. 3 The Lab-on-a-Chip Approach for Molecular Diagnostics / Xiaole Mao, Tony Jun Huang, Chih-Ming Ho -- Ch. 4 Nucleic Extraction and Amplification / Weimin Sun -- Ch. 5 General Procedures / Weimin Sun -- Ch. 6 Next-Generation Sequencing in Molecular Diagnostics / John R. ten Bosch, Wayne W. Grody -- Part II: Molecular Techniques for Anatomic and Surgical Pathology -- Ch. 7 In Situ Hybridization: Principles and Applications / Elizabeth R. Unger, Hiroaki Nitta, Daisy R. Lee, Thomas M. Grogan -- Part III: Quality Assurance, Regulatory, and Ethical Issues -- Ch. 8 Billing and Reimbursement for Molecular Diagnostics / Michael S. Watson, Michele Schoonmaker -- Ch. 9 Molecular Pathology and Infectious Diseases / Frederick L. Kiechle -- Ch. 10 Ethical Considerations in Molecular Diagnostics / Mary Kay Pelias, Robert M. Fineman -- Ch. 11 Quality Control, Assurance, Identification, and Standards / Matthew J. McGinniss -- Ch. 12 Regulatory Issues in Molecular Diagnostics / Wayne W. Grody.

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