Molecular imaging: basic principles and applications in biomedicalresearch

by Rudin, M., (Markus)

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Title Statements

Full title :Molecular imaging : basic principles and applications in biomedicalresearch / Markus Rudin, University of Zürich, Switzerland.

Summary

This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies. The second edition covers novel developments over recent years, in particularregarding imaging technologies (hybrid techniques) and novel reporter concepts.

Edition Statements

Publication Date:©2013
Edition:2nd edition

Publication Statements

Publisher(s):Imperial College Press
Place of Publication:London
Language:eng
Publication Date:©2013

The Physical Object

Description:1 ressource en ligne (618 pages) : : illustrations (certaines encouleur)

Edition Identifiers

ISBN:1848168578, 9781848168572
oclc:on1349227065
LC Classification:QP519.9.M64
Dewey Decimal:616.07/54

Introduction -- Methodologies -- Imaging techniques -- Molecular reporter systems -- Design of molecular imaging probes -- Applications -- Drug imaging -- Imaging gene expression -- Imaging the function of gene products -- Monitoring of cell migration.

Subjects

Biomedical Research Diagnostic Imaging Imagerie médicale Imagerie pour le diagnostic Imaging systems in medicine Livres numériques Molecular Probes Sondes moléculaires