Multiple sclerosis: a mechanistic view

by Minagar, Alireza

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Title Statements

Full title :Multiple sclerosis : a mechanistic view / edited by Alireza Minagar.

Edition Statements

Publication Date:©2016

Publication Statements

Publisher(s):Academic Press, an imprint of Elsevier
Place of Publication:Amsterdam
Language:eng
Publication Date:©2016

The Physical Object

Description:1 online resource (xvi, 521 pages)

Edition Identifiers

ISBN:0128010053, 9780128010051
oclc:ocn928992401
LC Classification:RC377
Dewey Decimal:616.834

Front Cover; MULTIPLE SCLEROSIS: A MECHANISTIC VIEW; Copyright; Contents; Contributors; Preface; 1 -- Clinical Manifestations of Multiple Sclerosis: An Overview; INTRODUCTION; MOTOR AND SENSORY MANIFESTATIONS; FATIGUE; COGNITIVE DECLINE; PSYCHIATRIC MANIFESTATIONS; OPTIC NEURITIS AND OTHER NEUROOPHTHALMOLOGIC MANIFESTATIONS; UVEITIS; UHTHOFF PHENOMENON; PULFRICH PHENOMENON; BRAIN STEM INVOLVEMENT IN MS; TRANSVERSE MYELITIS; CEREBELLAR INVOLVEMENT AND TREMOR IN MS; SEIZURES AND OTHER PAROXYSMAL FEATURES OF MS; PAINFUL SYNDROMES; BOWEL AND BLADDER DYSFUNCTION; MOVEMENT DISORDERS; References.

2 -- Novel Therapies for Multiple Sclerosis: A Mechanistic ViewINTRODUCTION; LAQUINIMOD; MONOCLONAL ANTIBODIES AS NOVEL THERAPIES FOR MS; ALEMTUZUMAB; DACLIZUMAB; OCRELIZUMAB; OFATUMUMAB; RITUXIMAB; THE CONCEPT OF REMYELINATION AS THERAPY FOR MS; AntiLINGO-1; rHIgM22; References; 3 -- Role of B Cells in the Pathogenesis of Multiple Sclerosis: Mechanisms of Action; Introduction; EVIDENCE OF B CELL INVOLVEMENT IN THE PATHOGENESIS OF MS AND FACTORS POINTING TO THE LIMITS OF T CELL ACTION; THE MECHANISM OF B CELL ACTION IN THE DEVELOPMENT AND PROGRESS OF MS; THE ROLE OF CLONALLY EXPANDED B CELLS.

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Subjects

HEALTH & FITNESS -- Diseases MEDICAL -- Clinical Medicine MEDICAL -- Diseases MEDICAL -- Evidence-Based Medicine MEDICAL -- Internal Medicine Multiple Sclerosis Multiple Sclerosis -- diagnosis Multiple Sclerosis -- physiopathology Multiple Sclerosis -- therapy Sclérose en plaques