Multiple sclerosis and CNS inflammatory disorders

by Goodman, Andrew D. Samkoff, Lawrence M.

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Title Statements

Full title :Multiple sclerosis and CNS inflammatory disorders / edited by Lawrence M. Samkoff, Andrew D. Goodman.

Summary

"Multiple Sclerosis and CNS Inflammatory Disorders is a practical guide to effective care of patients with multiple sclerosis and other neuroimmunologic disorders. It provides the scientific basis of multiple sclerosis, and its etiology, epidemiology and pathogenesis. It covers the diagnostic process, the course of the disease and prognosis, and the use of MRI in diagnosis and disease monitoring. Disease-modifying therapies, relapsing treatment algorithms, breakthrough RRMS, switching therapy, and progressive treatment algorithms are all discussed in detail. It also addresses multiple sclerosis in childhood and pregnancy, and includes assessment of 'alternative therapies'. This new addition to the Neurology in Practice series contains practical guidance and learning features: Algorithms and guidelines, 'Tips and Tricks' boxes on improving outcomes, 'Caution' warning boxes to avoiding problems, 'Science Revisited' - quick reminders of the basic science principles necessary for understanding. Multiple Sclerosis and CNS Neuroimmunologic Disorders is an ideal reference for neurologists in practice and training"--Provided by publisher.

Edition Statements

Publication Date:2014.

Publication Statements

Publisher(s):John Wiley & Sons, Inc
Place of Publication:Chichester, West Sussex, UK
Language:eng
Publication Date:2014.

The Physical Object

Description:1 online resource

Edition Identifiers

ISBN:9781118298657, 1118298659, 9781118298664, 1118298667, 9781118298633, 1118298632
oclc:ocn871228581
LC Classification:RC377
Dewey Decimal:616.8/34

""Title page""; ""Copyright page""; ""Contributors""; ""Series Foreword""; ""Preface""; ""1 Etiology""; ""Background""; ""Genes""; ""Gender effects: Genetic or biologic?""; ""The role of the environment""; ""Combining risk factors""; ""Conclusion""; ""Acknowledgment""; ""References""; ""2 Immunopathogenesis of Multiple Sclerosis""; ""What does the neuropathology of MS tell us about its pathogenesis?""; ""Gray matter pathology""; ""Multiple sclerosis as an autoimmune disease""; ""Candidates for the self-antigen inÂ multiple sclerosis""; ""Antigen spreading""; ""Epitope spreading""

""Outside-in versus inside-out?""""Lymphocyte trafficking into the CNS""; ""Role of T cells in MS""; ""Role of B cells and humoral immunity""; ""Role of microglia and macrophages""; ""Role of other cells: Dendritic cells andÂ astrocytes""; ""Role of cytokines""; ""What might trigger autoimmunity?""; ""Further Reading""; ""3 Diagnostic Process""; ""Introduction""; ""Clinical features of MS""; ""Diagnostic evaluation of MS""; ""Conclusion""; ""Further Reading""; ""4 MRI in Diagnosis and Disease Monitoring""; ""Introduction""; ""MRI at presentation""; ""MRI diagnostic criteria""

""MRI consensus protocol"""…

Subjects

Central nervous system -- Diseases Central Nervous System Diseases -- immu… HEALTH & FITNESS -- Diseases Internet resources MEDICAL -- Clinical Medicine MEDICAL -- Diseases MEDICAL -- Evidence-Based Medicine MEDICAL -- Internal Medicine Multiple Sclerosis Neurogenic Inflammation -- physiopathol… Sclérose en plaques Système nerveux central -- Immunologie