Narcolepsy: pathophysiology, diagnosis, and treatment

by Bassetti, Claudio L. Baumann, Christian R. Scammell, Thomas E.

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Title Statements

Full title :Narcolepsy : pathophysiology, diagnosis, and treatment / Christian R. Baumann, Claudio L. Bassetti, Thomas E. Scammell, editors.

Edition Statements

Publication Date:©2011.

Publication Statements

Publisher(s):Springer
Place of Publication:New York
Language:eng
Publication Date:©2011.

The Physical Object

Description:xv, 428 pages : : illustrations +

Edition Identifiers

ISBN:9781441983893, 1441983899, 9781441983909, 1441983902
oclc:ocn748763444
LC Classification:RC549
Dewey Decimal:616.8/498

pt. 1. Etiology of narcolepsy. Etiology and genetics of human narcolepsy / Emmanuel Mignot -- Narcolepsy : autoimmunity or secondary to infection? / Adriano Fontana, Heidemarie Gast, and Thomas Birchler -- Is narcolepsy a neurodegenerative disorder? / Christelle Peyron -- pt. 2. Neurochemistry of narcolepsy. The roles of hypocretin/orexin in narcolepsy, Parkinson's Disease, and normal behavior / Jerome Siegel -- Histamine in narcolepsy and excessive daytime sleepiness / Seiji Nishino -- Dopaminergic substrates underlying hypersomnia, sleepiness, and REM sleep expression / David B. Rye and Amanda A.H. Freeman -- The serotoninergic system in sleep and narcolepsy / Chloé Alexandre and Thomas E. Scammell -- Sleep homeostasis, adenosine, caffeine, and narcolepsy / Hans-Peter Landolt -- Prostaglandin D2: an endogenous somnogen/ Yoshihiro Urade and Osamu Hayaishi

pt. 3. The role of the hypocretins in sleep-wake regulation. The neurobiology of sleep-wake systems : an overview / Pierre-Hervé Luppi and Patrice Fort -- The hypocretins/orexins : master regulators of arousal and hyperarousal / Matthew E. Carter, Antoine Adamantidis, and Luis de Lecea -- Optogenetic probing of hypocretins' reg…