Neuroprogression and Staging in Bipolar Disorder

This title provides a comprehensive summary of the current state of the evidence regarding the use of staging systems in bipolar disorder. Edited by the leading researchers in the field, the book systematically covers the theoretical basis for staging, comparisons between different proposals, neurobiological underpinnings, the current evidence-base, limitations and future directions, and clinical implications and recommendations for practice. The book provides a solid and in-depth outline and thus aims to influence research and practice in the field of bipolar disorder.

Clinical staging in bipolar disorder, a historical perspective / Robert M. Post -- Staging systems in bipolar disorder / Ralph W. Kupka, Manon H.J. Hillegers, and Jan Scott -- Allostatic load and accelerated ageing in bipolar disorder / Iria Grande and Flavio Kapczinski -- Neuroprogression and biological underpinnings of staging in bipolar disorder / Gabriel R. Fries, Pedro V.S. Magalhães, Flavio Kapczinski and Michael Berk -- Functioning and illness progression in bipolar disorder / Anabel Martinez-Aran, Caterina del Mar Bonnin, Carla Torrent, Brisa Solé, Imma Torres, and Esther Jiménez -- Social cognition and staging in bipolar disorder / Sergio Strejilevich and Diego Martino -- Affective temperaments, potential latent stages of bipolar disorders / Gustavo H. Vázquez and Xenia Gonda -- Neuroimagining and illness progression / Benicio N. Frey, Luciano Minuzzi, Bartholomeus C.M. Haarman, and Roberto B. Sassi -- Biomarkers of illness progression in bipolar disorder / Aroldo A. Dargél and Marion Leboyer -- Childhood adversity and illness progression in bipolar disorder / Joana Bücker, Marcia Kauer-Sant'Anna, and Lakshmi N. Yatham -- Vascular and metabolic medical comorbidities and n…