Pediatric dialysis

The optimal management of children who receive dialysis therapy requires a thorough understanding of the multidisciplinary nature of their treatment. The multiple organ systems that are often impacted by acute and chronic impairment of kidney function makes the care of this patient population highly complex. This 3rd edition of Pediatric Dialysis provides authoritative and comprehensive information on all aspects of dialysis-related care for children to assist the clinician in achieving the best possible patient outcomes. Like the two preceding editions, the 3rd edition enlists experts from North America, South America, Europe, and Asia to provide their perspectives on virtually all issues pertaining to dialysis-related management for children, based on years of clinical and research experience. The book contains sections on all essential topics including when to initiate dialysis, peritoneal dialysis, hemodialysis, managing secondary complications, nutritional therapy, drugs and dialysis, dialysis outcomes, and transition to adult care. Each chapter has been thoroughly updated in terms of content and references. The book also includes several new chapters on topics such as remote patient monitoring, acute kidney injury management in the developing world, and antibiotic stewardship in the dialysis unit, maintaining the text's preeminent status as a worldwide source for pediatric dialysis care.

Intro -- Preface -- Acknowledgments -- Contents -- Contributors -- Part I: Essential Primers -- 1: Notes on the History of Dialysis Therapy in Children -- Introduction -- Peritoneal Dialysis -- Hemodialysis -- Patient Registries and Multicenter Studies -- Conclusion -- References -- 2: The Biology of Dialysis -- Introduction -- Biology of Uremic Toxicity -- Solute Removal Mechanisms in Extracorporeal Dialysis -- Diffusion -- Solute Removal by Convection -- Solute Removal by Internal Filtration -- New Membrane Designs for Enhanced Removal of Large Toxins -- Solute Removal by Adsorption

Peritoneal Dialysis: Biologic and Mass Transfer Considerations -- Factors Affecting Solute Transport -- Relationship Between Clearance and Mass Removal Rate Among Various Renal Replacement Therapies -- Clearance as a Dialyzer Performance Parameter -- Whole-Blood Clearance -- Blood Water and Plasma Clearance -- Dialysate-Side Clearance -- Whole-Body Clearance -- References -- 3: The Demographics of Dialysis in Children -- Introduction -- Sources of Demographic Data on Pediatric Dialysis Patients -- Incidence and Prevalence -- Access to Dialysis Around the World

Effect of Era on the Incidence and Pre…