Title Statements
- Full title :Polymorphism in Pharmaceutical Solids, Second Edition.
Summary
Using clear and practical examples, Polymorphism of Pharmaceutical Solids, Second Edition presents a comprehensive examination of polymorphic behavior in pharmaceutical development that is ideal for pharmaceutical development scientists and graduate students in pharmaceutical science. This edition focuses on pharmaceutical aspects of polymorphism and solvatomorphism, while systematically explaining their thermodynamic and structural origins. Topics include: Computational methodologies High-throughput screening methods Pharmaceutical cocrystals Thermally-induced and solution-mediated phase transformations Amorphous solids Crystallography preparation and characterization The amorphous state.
Read More ↓Edition Statements
- Publication Date:©2009.
- Edition:2nd ed
Publication Statements
- Publisher(s):CRC Press
- Place of Publication:New York
- Language:eng
- Publication Date:©2009.
The Physical Object
- Description:1 online resource (654 pages).
Edition Identifiers
- ISBN:9781420073225, 1420073222
- oclc:on1046084849
- LC Classification:RS201.S57P64 2009eb
- Dewey Decimal:615
Table of Contents
Front Cover -- Preface -- Contents -- Contributors -- PART I THERMODYNAMIC AND THEORETICAL ISSUES -- 1. Theory and Principles of Polymorphic Systems -- 2. Application of the Phase Rule to the Characterizationof Polymorphic and Solvatomorphic Systems -- 3. Computational Methodologies: Toward Crystal Structureand Polymorph Prediction -- PART II PREPARATIVE METHODS FOR POLYMORPHSAND SOLVATOMORPHS -- 4. Classical Methods of Preparation of Polymorphsand Alternative Solid Forms -- 5. Approaches to High-Throughput Physical FormScreening and Discovery -- PART III STRUCTURAL PROPERTIES OF POLYMORPHSAND SOLVATOMORPHS -- 6. Structural Aspects of Polymorphism -- 7. Structural Aspects of Solvatomorphic Systems -- 8. Pharmaceutical Co-crystals: A New Opportunityin Pharmaceutical Science for a Long-Known but Little-StudiedClass of Compounds -- PART IV CHARACTERIZATION METHODS FOR POLYMORPHSAND SOLVATOMORPHS -- 9. Thermoanalytical and Crystallographic Methods -- 10. Vibrational Spectroscopy -- 11. Solid-State Nuclear Magnetic Resonance Spectroscopy -- 12. Effects of Polymorphism and Solid-State Solvationon Solubility and Dissolution Rate -- PART V INTERCONVERSION OF POLYMORPHS AND SOLVATOMORPHS -…
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