Title Statements
- Full title :Principles of toxicology.
Edition Statements
- Publication Date:2015.
Publication Statements
- Publisher(s):CRC Press
- Place of Publication:Boca raton
- Language:eng
- Publication Date:2015.
The Physical Object
- Description:xvii, 437 pages : : illustrations ; : 24 cm
Edition Identifiers
- ISBN:1466503424, 9781466503427
- oclc:ocn913314706
- LC Classification:RA1211
- Dewey Decimal:615.9
Table of Contents
Machine generated contents note: Introduction -- Chemistry of Toxicants -- Toxicity Testing Methods -- Testing in Animals -- Human Data and Epidemiology -- Factors to be Considered in Planning Toxicity Testing -- Routes of Exposure -- Determining the Responses to Varying Doses of a Substance -- Timing of Exposure -- The LD50 (Median Lethal Dose) Experiment -- Testing -- Analysis -- Alternative Tests -- Categories of Toxicity -- No Observed Adverse Effect Levels -- Mixtures -- Toxicity, Hazard, and Risk -- Toxicity and Hazard -- The Role of Laboratory Testing in Estimation of Hazard -- Epidemiological Data -- Risk Assessment and Risk Management -- Case Study: Risk, Perception, and Vaccination -- Bibliography -- Introduction -- Pharmacokinetics and Toxicokinetics -- Absorption -- The Oral Route of Absorption -- Respiratory Route of Absorption -- Dermal Route of Absorption -- Distribution -- Elimination -- Toxicokinetic Models -- Mathematical Models of Elimination.
Note continued: Complicating Factors -- Clearance -- Absorption and Bioavailability -- Contrasting Kinetics of Lipophilic Substances -- Bibliography -- Introduction -- Primary Biotransformation (Phase I Reactions): Hydrol…
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