Protein engineering for therapeutics

by Verdine, Gregory L., (Gregory Lawrence) Wittrup, K. Dane

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This volume of looks at protein engineering for therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as antibodies, protein conjugates, peptides, enzymes and scaffolds.

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Title Statements

Full title :Protein engineering for therapeutics. / edited by K. Dane Wittrup, Gregory L. Verdine.

Summary

Edition Statements

Publication Date:2012.
Edition:1st ed

Publication Statements

Publisher(s):Academic
Place of Publication:San Diego, Calif
Language:eng
Publication Date:2012.

The Physical Object

Description:xliv, 348 pages, 6 unnumbered pages of plates : : illustrations (some color) ; : 23 cm.

Edition Identifiers

ISBN:9780123969620, 012396962X
oclc:ocn757491221
LC Classification:QP601
Dewey Decimal:615.3

Section IV. Peptides -- Stapled peptides for intracellular drug targets / Gregory L. Verdine and Gerard J. Hilinski -- Mapping of vascular ZIP codes by phage display / Tambet Teesalu, Kazuki N. Sugahara, and Erkki Ruoslahti -- Engineering cyclic peptide toxins / Richard J. Clark and David J. Craik -- Peptide discovery using bacterial display and flow cytometry / Jennifer A. Getz, Tobias D. Schoep, and Patrick S. Daugherty -- Section V. Scaffolds -- Designed ankyrin repeat proteins (DARPins) : from research to therapy / Rastislav Tamaskovic [and others] -- Target-binding proteins based on the 10th human fibronectin type III domain (10Fn3) / Shohei Koide, Akiko Koide, and Das̆a Lipovs̆ek -- Anticalins : small engineered binding proteins based on the lipocalin scaffold / Michaela Gebauer and Arne Skerra -- T cell receptor engineering / Jennifer D. Stone [and others] -- Engineering knottins as novel binding agents / Sarah J. Moore and Jennifer R. Cochran -- Section VI. Pharmacokinetics -- Practical theoretic guidance for the design of tumor-targeting agents / K. Dane Wittrup [and others] -- Reengineering biopharmaceuticals for targeted delivery across the blood-brain barrier / William M…

Subjects

Health and Fitness protein engineering Protein Engineering -- methods Protéines -- Emploi en thérapeutique Proteins -- pharmacokinetics Proteins -- therapeutic use Technologie des protéines