Title Statements
- Full title :Protein Therapeutics.
Edition Statements
- Publication Date:©2018
Publication Statements
- Publisher(s):John Wiley & Sons, Incorporated
- Place of Publication:Newark
- Language:eng
- Publication Date:©2018
Notes
9.3 The Components of an Antibody-Drug Conjugate.
The Physical Object
- Description:1 online resource (753 pages).
Edition Identifiers
- ISBN:9783527699131, 3527699139
- oclc:on1041144829
Table of Contents
Cover -- Title Page -- Copyright -- Contents -- Preface -- A Personal Foreword -- Acknowledgments -- Volume 1 -- Part I Introduction to Protein Therapeutics: Past and Present -- Chapter 1 Early Recombinant Protein Therapeutics -- 1.1 Introduction -- 1.2 The Birth of Genetic Engineering -- 1.3 Recombinant Human Insulin -- 1.3.1 The Race to Clone the Human Insulin Gene and to Produce Human Recombinant Insulin -- 1.3.2 Novo's Counter Strategy: Semisynthetic Human Insulin -- 1.3.3 Yeast Recombinant Insulin -- 1.4 Recombinant Human Growth Hormone -- 1.5 Recombinant Human Interferons -- 1.6 Recombinant Human Erythropoietin -- 1.7 Recombinant Tissue -- Type Plasminogen Activator -- 1.8 Recombinant Hepatitis B Virus (HBV) Vaccine -- 1.9 Postscript -- Acknowledgments -- References -- Chapter 2 Evolution of Antibody Therapeutics -- 2.1 Overview of Antibody Therapeutics Development -- 2.2 Polyclonal Antibodies -- Laying the Foundation for mAb Therapy -- 2.3 Evolution of Monoclonal Antibody Therapeutics -- 2.3.1 Chimeric and Humanized mAbs -- 2.3.2 Fully Human Antibodies -- 2.4 Fc Fusion Proteins -- 2.5 Evolution of Concepts in Antibody Pharmacology -- 2.5.1 Neutralization -- 2.5.2 From Killi…
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