Psychotic disorders: comprehensive conceptualization and treatments

"The definition of psychotic spectrum disorders such as schizophrenia has evolved with changing nosogy and scientific advancements over the last 200 years. Understanding both the historical evolution of the concept as well as recent changes reflected in the American Psychiatric Association's Diagnostic and Statistical Manual (DSM-5) as well as the National Institute of Health's (NIH) Research Domain Criteria (RDOC) framework are critical for informing current efforts to further update and refine the nosology of psychotic spectrum disorders. This chapter offers an overview of past classification schemes, current standards, and novel approaches to further improve the validity of these definitions through use of biomarkers, reverse nosologies, and digital phenotyping tools like smartphones and sensors"--

Cover -- Half title -- Psychotic Disorders -- Copyright -- Contents -- Preface ix -- Contributors xi -- SECTION 1 PHENOMENOLOGICAL CHARACTERISTICS AND DIMENSIONAL CONCEPTUALIZATION OF PSYCHOSIS -- 1. Conceptualization of psychosis in psychiatric nosology: past, present, and the future 3 -- 2. Historical epistemology of the "unitary psychosis" 12 -- 3. Dimensional conceptualization of psychosis 21 -- TRANSDIAGNOSTIC DIMENSIONS OF PSYCHOSIS -- 4. Applying Research Domain Criteria (RDoC) dimensions to psychosis 29 -- 5. Schizophrenia, schizoaffective disorder, bipolar disorder 38

6. Psychotic symptoms in bipolar disorder 46 -- 7. Major depressive disorder with psychotic features: confronting and resolving the dimensional challenge 50 -- 8. Psychosis in personality disorders 59 -- 9. Symptom network models of psychosis 70 -- PSYCHOSIS IN GENERAL MEDICAL CONDI TIONS AND ORGANIC BRAIN DISORDERS -- 10. Organic psychosis: phenotypic deviants or clues to schizophrenia? 81 -- 11. Epilepsy and psychosis 85 -- 12. Understanding sex differences in psychosis through the exploration of hormonal contributions 93 -- SECTION 2 PSYCHOSIS COURSE AND LIFETIME MANIFESTATIONS

13. Clinical phenomenolog…