Retinoblastoma protein

Retinoblastoma protein

by Santiago-Cardona, Pedro G.

Type Book
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This volume covers the mechanisms of pRb inactivation detailing repressive mechanisms commonly associated to cancer, and representative of the experimentally relevant tests used in the establishment of cancer diagnosis and prognosis. Chapters contain protocols and in-depth discussions for commonly used experimental approaches to assess the status and function of components of the pRb pathway, including pRb itself, in cell lines and biological samples. Written in the highly successful Methods in…

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Title Statements

  • Full title :Retinoblastoma protein / edited by Pedro G. Santiago-Cardona, ...

Summary

This volume covers the mechanisms of pRb inactivation detailing repressive mechanisms commonly associated to cancer, and representative of the experimentally relevant tests used in the establishment of cancer diagnosis and prognosis. Chapters contain protocols and in-depth discussions for commonly used experimental approaches to assess the status and function of components of the pRb pathway, including pRb itself, in cell lines and biological samples. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, The Retinoblastoma Protein aims to serve as a guide to assist molecular cancer biologists in their search for understanding of the molecular functions of this preeminent tumor suppressor.

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Edition Statements

  • Publication Date:C 2018

Publication Statements

  • Publisher(s):Humana Press
  • Place of Publication:New York
  • Language:eng
  • Publication Date:C 2018

Notes

Publié aussi sous forme numérique avec l'e-ISBN 978-1-4939-7565-5.

The Physical Object

  • Description:1 v. (XI-200 p.) : : illustrations ; : 26 cm

Edition Identifiers

  • ISBN:9781493975648, 1493975641
  • oclc:on1030299913

Subjects

Gènes du rétinoblastome Protéines suppresseurs de tumeurs Rétinoblastome

Writers

Santiago-Cardona, Pedro G.

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