RNA modification

RNA modification

by He, Chuan

Type Book
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<I> RNA Modification</i> provides a useful examination of the science and its role in biological regulation, the current frontier of life science research, and includes various RNA modications and their role in gene expression. It represents the most up-to-date knowledge and protocols available today. <br><br><ul><li>Dynamic RNA modifications and their roles in biological regulation are the current frontier of life science research</li><li>This volume of Methods in Enzymology represents up to d…

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Title Statements

  • Full title :RNA modification / edited by Chuan He.

Summary

<I> RNA Modification</i> provides a useful examination of the science and its role in biological regulation, the current frontier of life science research, and includes various RNA modications and their role in gene expression. It represents the most up-to-date knowledge and protocols available today. <br><br><ul><li>Dynamic RNA modifications and their roles in biological regulation are the current frontier of life science research</li><li>This volume of Methods in Enzymology represents up to date knowledge and protocols</li></ul>

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Edition Statements

  • Publication Date:©2015

Publication Statements

  • Publisher(s):Academic Press
  • Place of Publication:Amsterdam, [Netherlands]
  • Language:eng
  • Publication Date:©2015

Notes

Description based upon print version of record.

5 Protocol 2: 6mA-CLIP-exo Sequencing

The Physical Object

  • Description:1 online resource (760 p.).

Edition Identifiers

  • ISBN:0128023317, 9780128023310, 0128021926, 9780128021927
  • oclc:on1159615402
  • LC Classification:QH450.25
  • Dewey Decimal:572.88

Table of Contents

Cover image; Title page; Table of Contents; Copyright; Contributors; Preface; Chapter One: Methodology for the High-Throughput Identification and Characterization of tRNA Variants That Are Substrates for a tRNA Decay Pathway; Abstract; 1 Introduction; 2 High-Throughput Identification of tRNA Substrates Degraded by the RTD Pathway; 3 Measurement of tRNA Levels of RTD Substrate SUP4oc Variants in the Presence of WT tRNATyr; 4 Conclusions and Additional Applications of These Approaches; Acknowledgments

Chapter Two: Nucleoside Analysis by Hydrophilic Interaction Liquid Chromatography Coupled with Mass SpectrometryAbstract; 1 Introduction; 2 Nucleoside Preparation for LC/MS Analysis; 3 HILIC/ESI-MS for Total Nucleosides; 4 HILIC/ESI-MS Versus RPC/ESI-MS for Nucleoside Analysis; 5 Profiling of Modified Nucleosides in HILIC/ESI-MS; 6 Discussion; Acknowledgments; Chapter Three: A Platform for Discovery and Quantification of Modified Ribonucleosides in RNA: Application to Stress-Induced Reprogramming of tRNA Modifications; Abstract; 1 Introduction; 2 Methods; 3 Discussion; Acknowledgments

Chapter Four: Recognition of Specified RNA Modifications by the Innate Immune SystemAbstract; 1 Intr…

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