Somatostatin

by Srikant, Coimbatore B.

Type Book

Rate 0.0 /5

Details

Files

Reviews

Download

Title Statements

Full title :Somatostatin / edited by Coimbatore B. Srikant.

Summary

This volume presents the state-of-the-art description of the current understanding of the biology of somatostatin including its gene regulation, prosomatostatin processing, cellular effects, somatostatin receptor subtypes, mechanism of action, signal transduction, regulation of cell growth and apoptosis, design and use of receptor subtype-selective somatostatin analogs, derivatives of somatostatin analogs tagged with radionuclides/chemotoxins, and their clinical relevance in the diagnosis and treatment of cancer. Each chapter is written by expert(s) active in somatostatin research (experimental and/or clinical). It will serve as the only single one-stop source of the most up to date information on the basic and clinical aspects of the biology of somatostatin and its receptors.

Edition Statements

Publication Date:2004.

Publication Statements

Publisher(s):Springer US
Place of Publication:Boston, MA
Language:eng
Publication Date:2004.

The Physical Object

Description:1 online resource (xvi, 311 pages).

Edition Identifiers

ISBN:9781402077999, 1402077998, 9781402080333, 1402080336
DOI:10.1007/b112847
oclc:ocn853256808
LC Classification:RM1-950
Dewey Decimal:615

Somatostatin Gene Structure and Regulation -- Processing and Intracellular Targeting of Somatostatin -- Cortistatin- A Novel Member of the Somatostatin Gene Family -- Molecular Evolution of Somatostatin Genes -- Altered Patterns of Growth Hormone Secretion in Somatostatin Knockout Mice -- Somatostatin Receptor Gene Family -- Subtype Selectivity for Ligand Binding -- Expression of Somatostatin Receptors in Human Tissues in Health and Disease -- Coexpression of Multiple Somatostatin Receptors in Individual Cells -- Somatostatin Receptor Subtype Selectivity for Cytotoxic and Cytostatic Signaling -- Somatostatin Receptor Signaling via Protein Tyrosine Phosphatases -- Expression and Function of Somatostatin and its Receptors in Immune Cells -- Physiology of Somatostatin Receptors: From Genetics to Molecular Analysis -- Somatostatin Receptor Imaging -- Somatostatin Analogs in the Treatment of Pituitary Tumors -- Somatostatin Receptor Targeted-Radio-Ablation of Tumors -- Somatostatin Analogue Therapy of Neuro-Endocrine Gastro-Entero Pancreatic Tumors -- Vascular Effects of Somatostatin -- The Use of Somatostatin Analogues in Diabetic Retinopathy -- Somatostatin and its Receptors: Past, P…