Stem cells handbook

Stem Cells Handbook, second edition, emphasizesthe advances in understanding and working with embryonic and fetal stem cells as well as induced pluripotent stem cells that show the most promise for clinical use. This new edition has been completely rewritten and updated to reflect the significant advances made in this field since publication of the first edition in 2004. The thirty-six chapters in this book all written by recognized experts in Stem Cell research reflect the tremendous progress in the understanding of stem cell biology and the appreciation of the potential for using stem cells for therapy of cancer, aging, injury and congenital diseases. Arguably the biggest advances have been made in obtaining different populations of stem cells, inducing mature cells to act like stem cells, and the ever-critical issue of how to get these stem cells to expand and differentiate into the tissue precursor cells that then can be used to replace lost of damaged tissues. No less exciting are the recent advances in understanding how stem cells function to maintain tissue integrity and how to use this knowledge to prevent developmental abnormalities. Other key topics discussed include: properties of tissue stem cells, transplantation of stem cells, the stem cell as a target for cancer treatment and prevention.--[Source inconnue].

Titre de l'écran-titre (visionné le 8 novembre 2013).

Introduction to stem cells / Rob Burgess -- Contemporary ethical issues in stem cell research / Valerie Gutmann Koch, Beth E. Roxland, Barbara Pohl and Sarah K. Keech -- Part I. Embryonic/fetal stem cells. Stem cells from early mammalian embryos / Anna-Katerina Hadjantonakis, Svetlana Gavrilov, Panagiotis Xenopoulos, and Virginia E. Papaioannou ; Quantitative approaches to model pluripotency and differentiation in stem cells / Dmitri Papatsenko, Huilei Xu, Avi Ma'ayan, and Ihor Lemischka ; Growth dynamics of fetal human neural stem cells / Walter D. Niles, Dustin R. Wakemann, and Evan Y. Snyder ; Immunobiology of embryonic and induced pluripotent stem cell transplantation / Eleanor M. Bolton, J. Andrew Bradley, and Craig J. Taylor -- Part II. Pluripotent stem cells. Urodele limb regeneration: mechanisms of blastema formation and growth / David L. Stocum ; Mechanism of miR-302-mediated iPS cell generation / Shi-Lung Lin ; Bioreactor expansion of pluripotent stem cells / Jaymi T. Taiani, Mehdi Shafa, and Derrick E. Rancourt ; Generation of hepatocyte-like cells from human pluripotent stem cells / Fallon K. Noto and Stephen A. Duncan ; Neural differentiation from pluripotent stem cel…